Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine.

Jangra, Sonia; De Vrieze, Jana; Choi, Angela; Rathnasinghe, Raveen; Laghlali, Gabriel; Uvyn, Annemiek; Van Herck, Simon; Nuhn, Lutz; Deswarte, Kim; Zhong, Zifu; Sanders, Niek; Lienenklaus, Stefan; David, Sunil; Strohmeier, Shirin; Amanat, Fatima; Krammer, Florian; Hammad, Hamida; Lambrecht, Bart N; Coughlan, Lynda; García-Sastre, Adolfo; De Geest, Bruno G; Schotsaert, Michael

Jangra, Sonia; De Vrieze, Jana; Choi, Angela; Rathnasinghe, Raveen; Laghlali, Gabriel; Uvyn, Annemiek; Van Herck, Simon; Nuhn, Lutz; Deswarte, Kim; Zhong, Zifu; Sanders, Niek; Lienenklaus, Stefan; David, Sunil; Strohmeier, Shirin; Amanat, Fatima; Krammer, Florian; Hammad, Hamida; Lambrecht, Bart N; Coughlan, Lynda; García-Sastre, Adolfo; De Geest, Bruno G; Schotsaert, Michael.

Afiliación

Jangra S; Department of Microbiology, Icahn School of Medicine at Mount Sinai New York, NY, USA.
De Vrieze J; Department of Pharmaceutics, Ghent University, Ghent, Belgium.
Choi A; Department of Microbiology, Icahn School of Medicine at Mount Sinai New York, NY, USA.
Rathnasinghe R; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Laghlali G; Department of Microbiology, Icahn School of Medicine at Mount Sinai New York, NY, USA.
Uvyn A; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Van Herck S; Department of Microbiology, Icahn School of Medicine at Mount Sinai New York, NY, USA.
Nuhn L; Department of Pharmaceutics, Ghent University, Ghent, Belgium.
Deswarte K; Department of Pharmaceutics, Ghent University, Ghent, Belgium.
Zhong Z; Department of Pharmaceutics, Ghent University, Ghent, Belgium.
Sanders N; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for inflammation research, Ghent, Belgium.
Lienenklaus S; Laboratory for Gene Therapy, Ghent University, Merelbeke, Belgium.
David S; Laboratory for Gene Therapy, Ghent University, Merelbeke, Belgium.
Strohmeier S; Institute for Laboratory Animal Science, Institute of Immunology, Hannover Medical School, Hannover, Germany.
Amanat F; Virovax, Lawrance, KS, USA.
Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai New York, NY, USA.
Hammad H; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Lambrecht BN; Department of Microbiology, Icahn School of Medicine at Mount Sinai New York, NY, USA.
Coughlan L; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai New York, NY, USA.
De Geest BG; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for inflammation research, Ghent, Belgium.
Schotsaert M; Department of Internal Medicine and Pediatrics, Ghent University, VIB Center for inflammation research, Ghent, Belgium.

bioRxiv ; 2020 Oct 23.

Article en En | MEDLINE | ID: mdl-33106810

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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: BioRxiv Año: 2020 Tipo del documento: Article

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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: BioRxiv Año: 2020 Tipo del documento: Article