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Depletion of essential isoprenoids and ER stress induction following acute liver-specific deletion of HMG-CoA reductase.
De Giorgi, Marco; Jarrett, Kelsey E; Burton, Jason C; Doerfler, Alexandria M; Hurley, Ayrea; Li, Ang; Hsu, Rachel H; Furgurson, Mia; Patel, Kalyani R; Han, Jun; Borchers, Christoph H; Lagor, William R.
Afiliación
  • De Giorgi M; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA.
  • Jarrett KE; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA; Integrative Molecular and Biomedical Sciences Graduate Program, Baylor College of Medicine, Houston, TX, USA.
  • Burton JC; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA; Integrative Molecular and Biomedical Sciences Graduate Program, Baylor College of Medicine, Houston, TX, USA.
  • Doerfler AM; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA.
  • Hurley A; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA.
  • Li A; Department of Bioengineering, Rice University, Houston, TX, USA.
  • Hsu RH; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA.
  • Furgurson M; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA.
  • Patel KR; Department of Pathology, Texas Children's Hospital, Houston, TX, USA.
  • Han J; Genome British Columbia Proteomics Centre, University of Victoria, Victoria, British Columbia, Canada.
  • Borchers CH; Proteomics Centre, Segal Cancer Centre, Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, Quebec, Canada; Gerald Bronfman Department of Oncology, Jewish General Hospital, Montreal, Quebec, Canada; Department of Data Intensive Science and Engineering, Skolkovo Institute of S
  • Lagor WR; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA. Electronic address: lagor@bcm.edu.
J Lipid Res ; 61(12): 1675-1686, 2020 12.
Article en En | MEDLINE | ID: mdl-33109681
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Terpenos / Estrés del Retículo Endoplásmico / Hidroximetilglutaril-CoA Reductasas / Hígado Idioma: En Revista: J Lipid Res Año: 2020 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Terpenos / Estrés del Retículo Endoplásmico / Hidroximetilglutaril-CoA Reductasas / Hígado Idioma: En Revista: J Lipid Res Año: 2020 Tipo del documento: Article