CD73 regulates hepatic stellate cells activation and proliferation through Wnt/ß-catenin signaling pathway.

Jia, Wen-Qian; Zhou, Tao-Cheng; Dai, Jing-Wen; Liu, Zhen-Ni; Zhang, Ya-Fei; Zang, Dan-Dan; Lv, Xiong-Wen

Jia, Wen-Qian; Zhou, Tao-Cheng; Dai, Jing-Wen; Liu, Zhen-Ni; Zhang, Ya-Fei; Zang, Dan-Dan; Lv, Xiong-Wen.

Afiliación

Jia WQ; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, China; The Key Laboratory of Anti-inflammatory and Immune Medicines, Ministry of Education, Hefei, China; Institute for Liver Diseases of Anhui M
Zhou TC; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, China; The Key Laboratory of Anti-inflammatory and Immune Medicines, Ministry of Education, Hefei, China; Institute for Liver Diseases of Anhui M
Dai JW; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, China; The Key Laboratory of Anti-inflammatory and Immune Medicines, Ministry of Education, Hefei, China; Institute for Liver Diseases of Anhui M
Liu ZN; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, China; The Key Laboratory of Anti-inflammatory and Immune Medicines, Ministry of Education, Hefei, China; Institute for Liver Diseases of Anhui M
Zhang YF; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, China; The Key Laboratory of Anti-inflammatory and Immune Medicines, Ministry of Education, Hefei, China; Institute for Liver Diseases of Anhui M
Zang DD; The Center for Scientific Research of Anhui Medical University, China.
Lv XW; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, China; The Key Laboratory of Anti-inflammatory and Immune Medicines, Ministry of Education, Hefei, China; Institute for Liver Diseases of Anhui M

Eur J Pharmacol ; 890: 173667, 2021 Jan 05.

Article en En | MEDLINE | ID: mdl-33121948

Asunto(s)

5'-Nucleotidasa/biosíntesis; Proliferación Celular/fisiología; Células Estrelladas Hepáticas/metabolismo; Vía de Señalización Wnt/fisiología; 5'-Nucleotidasa/antagonistas & inhibidores; 5'-Nucleotidasa/deficiencia; Adenosina Difosfato/análogos & derivados; Adenosina Difosfato/farmacología; Animales; Línea Celular; Proliferación Celular/efectos de los fármacos; Células Cultivadas; Células Estrelladas Hepáticas/efectos de los fármacos; Masculino; Ratones; Ratones Endogámicos C57BL; Ratas; Vía de Señalización Wnt/efectos de los fármacos

Palabras clave

Alcoholic liver fibrosis (ALF); Ecto-5'-nucleotidase (CD73); Hepatic stellate cells (HSCs); Proliferation; Wnt/ß-catenin pathway

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: 5'-Nucleotidasa / Proliferación Celular / Células Estrelladas Hepáticas / Vía de Señalización Wnt Idioma: En Revista: Eur J Pharmacol Año: 2021 Tipo del documento: Article

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