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mTORC1 activation in lung mesenchyme drives sex- and age-dependent pulmonary structure and function decline.
Obraztsova, Kseniya; Basil, Maria C; Rue, Ryan; Sivakumar, Aravind; Lin, Susan M; Mukhitov, Alexander R; Gritsiuta, Andrei I; Evans, Jilly F; Kopp, Meghan; Katzen, Jeremy; Robichaud, Annette; Atochina-Vasserman, Elena N; Li, Shanru; Carl, Justine; Babu, Apoorva; Morley, Michael P; Cantu, Edward; Beers, Michael F; Frank, David B; Morrisey, Edward E; Krymskaya, Vera P.
Afiliación
  • Obraztsova K; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Basil MC; Lung Biology Institute, University of Pennsylvania, Philadelphia, PA, USA.
  • Rue R; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Sivakumar A; Lung Biology Institute, University of Pennsylvania, Philadelphia, PA, USA.
  • Lin SM; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Mukhitov AR; Children Hospital of Philadelphia, Philadelphia, PA, USA.
  • Gritsiuta AI; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Evans JF; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Kopp M; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Katzen J; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Robichaud A; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Atochina-Vasserman EN; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Li S; Lung Biology Institute, University of Pennsylvania, Philadelphia, PA, USA.
  • Carl J; SCIREQ Inc., Montreal, QC, Canada.
  • Babu A; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Morley MP; Lung Biology Institute, University of Pennsylvania, Philadelphia, PA, USA.
  • Cantu E; Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA, USA.
  • Beers MF; Lung Biology Institute, University of Pennsylvania, Philadelphia, PA, USA.
  • Frank DB; Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA, USA.
  • Morrisey EE; Lung Biology Institute, University of Pennsylvania, Philadelphia, PA, USA.
  • Krymskaya VP; Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA, USA.
Nat Commun ; 11(1): 5640, 2020 11 06.
Article en En | MEDLINE | ID: mdl-33159078
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Linfangioleiomiomatosis / Diana Mecanicista del Complejo 1 de la Rapamicina / Pulmón / Mesodermo Tipo de estudio: Prognostic_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Linfangioleiomiomatosis / Diana Mecanicista del Complejo 1 de la Rapamicina / Pulmón / Mesodermo Tipo de estudio: Prognostic_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article