The Anti-inflammatory Effects of Lignan Glycosides from Cistanche tubulosa stems on LPS/IFN-Î³-induced RAW264.7 Macrophage Cells via PI3K/ AKT Pathway.

Guo, Jinhan; Tang, Shuming; Miao, Yuyang; Ge, Lanlan; Xu, Junfa; Zeng, Xiaobin

Guo, Jinhan; Tang, Shuming; Miao, Yuyang; Ge, Lanlan; Xu, Junfa; Zeng, Xiaobin.

Afiliación

Guo J; Ultrasonography Department of Longhua Branch, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China.
Tang S; Department of Clinical Laboratory, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University), Shenzhen 518020, Guangdong, China.
Miao Y; Center Lab of Longhua Branch and Department of Infectious Disease, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China.
Ge L; Center Lab of Longhua Branch and Department of Infectious Disease, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China.
Xu J; Institute of Laboratory Medicine, Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Guangdong Medical College, Dongguan 523808, Guangdong, China.
Zeng X; Center Lab of Longhua Branch and Department of Infectious Disease, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China.

Curr Pharm Biotechnol ; 22(10): 1380-1391, 2021.

Article en En | MEDLINE | ID: mdl-33238839

Asunto(s)

Cistanche; Lignanos; Animales; Antiinflamatorios/farmacología; Cistanche/metabolismo; Glicósidos/farmacología; Lignanos/farmacología; Lipopolisacáridos; Macrófagos/metabolismo; Ratones; Simulación del Acoplamiento Molecular; FN-kappa B/metabolismo; Óxido Nítrico/metabolismo; Óxido Nítrico Sintasa de Tipo II; Fosfatidilinositol 3-Quinasas/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Células RAW 264.7

Palabras clave

Cistanche tubulosa; PI3K/AKT.; RAW264.7; anti-inflammatory activity; lignan glycosides; structure-activity relationship

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Lignanos / Cistanche Idioma: En Revista: Curr Pharm Biotechnol Asunto de la revista: BIOTECNOLOGIA / FARMACOLOGIA Año: 2021 Tipo del documento: Article

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