Interstitial pneumonia with autoimmune features in a patient with melanoma differentiation-associated gene 5 (MDA5) antibody.
BMJ Case Rep
; 13(11)2020 Nov 30.
Article
en En
| MEDLINE
| ID: mdl-33257351
ABSTRACT
Melanoma differentiation-associated gene 5 (MDA5) antibody, also known as anti-CADM140 antibody is recognised to be associated with rapidly progressive interstitial lung disease, which can be fatal within 3 months. It is also known to be associated with amyopathic dermatomyositis. We report a case of MDA5 antibody-associated interstitial pneumonia with autoimmune features, without cutaneous features of dermatomyositis, in a Sudanese patient with dual positive antibodies to Ro52. The patient notably had several features associated with poor prognosis, including age, high serum ferritin level, anti-Ro52 antibodies and progressive lung infiltrates during treatment.
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Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Autoanticuerpos
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Enfermedades Pulmonares Intersticiales
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Helicasa Inducida por Interferón IFIH1
Tipo de estudio:
Diagnostic_studies
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Etiology_studies
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Prognostic_studies
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Risk_factors_studies
Idioma:
En
Revista:
BMJ Case Rep
Año:
2020
Tipo del documento:
Article