Binding-Mediated Formation of Ribonucleoprotein Corona for Efficient Delivery and Control of CRISPR/Cas9.

Wu, Jinjun; Peng, Hanyong; Lu, Xiufen; Lai, Maode; Zhang, Hongquan; Le, X Chris

Wu, Jinjun; Peng, Hanyong; Lu, Xiufen; Lai, Maode; Zhang, Hongquan; Le, X Chris.

Afiliación

Wu J; Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, T6G 2G3, Canada.
Peng H; Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, T6G 2G3, Canada.
Lu X; Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, T6G 2G3, Canada.
Lai M; Department of Pathology, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310058, China.
Zhang H; Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, T6G 2G3, Canada.
Le XC; Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, T6G 2G3, Canada.

Angew Chem Int Ed Engl ; 60(20): 11104-11109, 2021 05 10.

Article en En | MEDLINE | ID: mdl-33354860

Asunto(s)

Proteína 9 Asociada a CRISPR/química; Corona de Proteínas/química; Ribonucleoproteínas/química; Proteína 9 Asociada a CRISPR/metabolismo; Sistemas CRISPR-Cas; Humanos; Tamaño de la Partícula; Unión Proteica

Palabras clave

CRISPR/Cas9; gene editing; gold nanoparticles; protein corona; protein delivery

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Ribonucleoproteínas / Corona de Proteínas / Proteína 9 Asociada a CRISPR Idioma: En Revista: Angew Chem Int Ed Engl Año: 2021 Tipo del documento: Article

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