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Study on the secondary metabolites of grasshopper-derived fungi Arthrinium sp. NF2410.
Li, Wei; Wei, Jing; Chen, Dao-Ying; Wang, Mei-Jing; Sun, Yang; Jiao, Fang-Wen; Jiao, Rui-Hua; Tan, Ren-Xiang; Ge, Hui-Ming.
Afiliación
  • Li W; State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, School of Life Sciences, Nanjing University, Nanjing 210023, China.
  • Wei J; State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, School of Life Sciences, Nanjing University, Nanjing 210023, China.
  • Chen DY; State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, School of Life Sciences, Nanjing University, Nanjing 210023, China.
  • Wang MJ; State Key Laboratory of Pharmaceutical Biotechnology, Department of Biotechnology and Pharmaceutical Sciences, School of Life Science, Nanjing University, Nanjing 210023, China.
  • Sun Y; State Key Laboratory of Pharmaceutical Biotechnology, Department of Biotechnology and Pharmaceutical Sciences, School of Life Science, Nanjing University, Nanjing 210023, China.
  • Jiao FW; State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, School of Life Sciences, Nanjing University, Nanjing 210023, China.
  • Jiao RH; State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, School of Life Sciences, Nanjing University, Nanjing 210023, China.
  • Tan RX; State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, School of Life Sciences, Nanjing University, Nanjing 210023, China; State Key Laboratory Cultivation Base for TCM Quality and Efficacy, Nanjing University of Chinese Medicine, Nanjing 210023, China. Electroni
  • Ge HM; State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, School of Life Sciences, Nanjing University, Nanjing 210023, China. Electronic address: hmge@nju.edu.cn.
Chin J Nat Med ; 18(12): 957-960, 2020 Dec.
Article en En | MEDLINE | ID: mdl-33357727
ABSTRACT
Two new 2-carboxymethyl-3-hexyl-maleic anhydride derivatives, arthrianhydride A (1) and B (2), along with three known compounds 3-5, were isolated from the fermentation broth of a grasshopper-associated fungus Arthrinium sp. NF2410. The structures of new compounds 1 and 2 were determined based on the analysis of the HR-ESI-MS and NMR spectroscopic data. Furthermore, compounds 1 and 2 were evaluated on inhibitory activity against the enzyme SHP2 and both of them showed moderate inhibitory activity against SHP2.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Inhibidores Enzimáticos / Hongos / Saltamontes / Anhídridos Idioma: En Revista: Chin J Nat Med Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Inhibidores Enzimáticos / Hongos / Saltamontes / Anhídridos Idioma: En Revista: Chin J Nat Med Año: 2020 Tipo del documento: Article