Preliminary evidence on abatacept safety and efficacy in refractory juvenile localized scleroderma.

Li, Suzanne C; Torok, Kathryn S; Ishaq, Sarah S; Buckley, Mary; Edelheit, Barbara; Ede, Kaleo C; Liu, Christopher; Rabinovich, C Egla

Li, Suzanne C; Torok, Kathryn S; Ishaq, Sarah S; Buckley, Mary; Edelheit, Barbara; Ede, Kaleo C; Liu, Christopher; Rabinovich, C Egla.

Afiliación

Li SC; Department of Pediatrics, Joseph M. Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack Meridian School of Medicine, Hackensack, NJ, USA.
Torok KS; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Ishaq SS; Department of Biochemistry, Montclair State University, Montclair, NJ, USA.
Buckley M; Department of Pediatrics, Duke Children's Hospital and Health Center, Duke University School of Medicine, Durham, NC, USA.
Edelheit B; Department of Pediatrics, Connecticut Children's Medical Center, Hartford, CT, USA.
Ede KC; Department of Pediatrics, Phoenix Children's Hospital, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA.
Liu C; Department of Biochemistry, Montclair State University, Montclair, NJ, USA.
Rabinovich CE; Department of Pediatrics, Duke Children's Hospital and Health Center, Duke University School of Medicine, Durham, NC, USA.

Rheumatology (Oxford) ; 60(8): 3817-3825, 2021 08 02.

Article en En | MEDLINE | ID: mdl-33369667

Asunto(s)

Abatacept/uso terapéutico; Antirreumáticos/uso terapéutico; Esclerodermia Localizada/tratamiento farmacológico; Esclerodermia Sistémica/tratamiento farmacológico; Adolescente; Niño; Estudios de Cohortes; Femenino; Humanos; Masculino; Metotrexato/uso terapéutico; Ácido Micofenólico/uso terapéutico; Estudios Retrospectivos; Insuficiencia del Tratamiento; Resultado del Tratamiento

Palabras clave

Localized scleroderma; biologic treatment; methotrexate; morphea; musculoskeletal activity; pediatric rheumatology; refractory; treatment failure

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Esclerodermia Localizada / Esclerodermia Sistémica / Antirreumáticos / Abatacept Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Idioma: En Revista: Rheumatology (Oxford) Asunto de la revista: REUMATOLOGIA Año: 2021 Tipo del documento: Article

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