Acute Peripheral Inflammation Increases Plasma Concentration of Hypoglycemic Agent Nateglinide with Decreased Hepatic Drug-Metabolizing Activity in Rats.

Kojina, Moeko; Suzuki, Keiichiro; Nishiwaki, Akane; Aiba, Tetsuya

Kojina, Moeko; Suzuki, Keiichiro; Nishiwaki, Akane; Aiba, Tetsuya.

Afiliación

Kojina M; Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University.
Suzuki K; Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University.
Nishiwaki A; Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University.
Aiba T; Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University.

Biol Pharm Bull ; 44(1): 96-102, 2021.

Article en En | MEDLINE | ID: mdl-33390555

Asunto(s)

Hipoglucemiantes/sangre; Inflamación/sangre; Microsomas Hepáticos/efectos de los fármacos; Microsomas Hepáticos/metabolismo; Nateglinida/sangre; Animales; Carragenina/toxicidad; Hipoglucemiantes/farmacología; Inflamación/inducido químicamente; Masculino; Nateglinida/farmacología; Ratas; Ratas Wistar

Palabras clave

CYP2C11; acute inflammation; hepatic drug metabolism; nateglinide

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Microsomas Hepáticos / Nateglinida / Hipoglucemiantes / Inflamación Tipo de estudio: Prognostic_studies Idioma: En Revista: Biol Pharm Bull Asunto de la revista: BIOQUIMICA / FARMACOLOGIA Año: 2021 Tipo del documento: Article

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