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Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer's disease.
Ellwanger, Daniel C; Wang, Shoutang; Brioschi, Simone; Shao, Zhifei; Green, Lydia; Case, Ryan; Yoo, Daniel; Weishuhn, Dawn; Rathanaswami, Palaniswami; Bradley, Jodi; Rao, Sara; Cha, Diana; Luan, Peng; Sambashivan, Shilpa; Gilfillan, Susan; Hasson, Samuel A; Foltz, Ian N; van Lookeren Campagne, Menno; Colonna, Marco.
Afiliación
  • Ellwanger DC; Genome Analysis Unit, Amgen Research, Amgen Inc., South San Francisco, CA 94080.
  • Wang S; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110.
  • Brioschi S; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110.
  • Shao Z; Department of Inflammation and Oncology, Amgen Research, Amgen Inc., South San Francisco, CA 94080.
  • Green L; Department of Biologics Discovery, Amgen Research, Amgen Inc., Burnaby, BC, V5A1V7 Canada.
  • Case R; Discovery Attribute Sciences, Amgen Research, Amgen Inc., South San Francisco, CA 94080.
  • Yoo D; Department of Biologics Optimization, Amgen Research, Amgen Inc., Thousand Oaks, CA 91320.
  • Weishuhn D; Department of Biologics Discovery, Amgen Research, Amgen Inc., Burnaby, BC, V5A1V7 Canada.
  • Rathanaswami P; Department of Biologics Discovery, Amgen Research, Amgen Inc., Burnaby, BC, V5A1V7 Canada.
  • Bradley J; Department of Neuroscience, Amgen Research, Amgen Inc., Cambridge, MA 02142.
  • Rao S; Department of Inflammation and Oncology, Amgen Research, Amgen Inc., South San Francisco, CA 94080.
  • Cha D; Department of Neuroscience, Amgen Research, Amgen Inc., Cambridge, MA 02142.
  • Luan P; Department of Translational Safety and Bioanalytical Sciences, Amgen Research, Amgen Inc., Thousand Oaks, CA 91320.
  • Sambashivan S; Genome Analysis Unit, Amgen Research, Amgen Inc., South San Francisco, CA 94080.
  • Gilfillan S; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110.
  • Hasson SA; Department of Neuroscience, Amgen Research, Amgen Inc., Cambridge, MA 02142.
  • Foltz IN; Department of Biologics Discovery, Amgen Research, Amgen Inc., Burnaby, BC, V5A1V7 Canada.
  • van Lookeren Campagne M; Department of Inflammation and Oncology, Amgen Research, Amgen Inc., South San Francisco, CA 94080; mvanlook@amgen.com mcolonna@wustl.edu.
  • Colonna M; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110; mvanlook@amgen.com mcolonna@wustl.edu.
Proc Natl Acad Sci U S A ; 118(3)2021 01 19.
Article en En | MEDLINE | ID: mdl-33446504
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Encéfalo / Glicoproteínas de Membrana / Receptores Inmunológicos / Microglía / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Encéfalo / Glicoproteínas de Membrana / Receptores Inmunológicos / Microglía / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article