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Apoptotic activities of brusatol in human non-small cell lung cancer cells: Involvement of ROS-mediated mitochondrial-dependent pathway and inhibition of Nrf2-mediated antioxidant response.
Xie, Jianhui; Lai, Zhengquan; Zheng, Xinghan; Liao, Huijun; Xian, Yanfang; Li, Qian; Wu, Jingjing; Ip, Siupo; Xie, Youliang; Chen, Jiannan; Su, Ziren; Lin, Zhixiu; Yang, Xiaobo.
Afiliación
  • Xie J; Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, P.R. China.
  • Lai Z; Department of Pharmacy, Shenzhen University General Hospital, Shenzhen University, Shenzhen 518000, P.R. China.
  • Zheng X; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, P.R. China.
  • Liao H; Department of Clinical Pharmacy and Pharmaceutical Services, Huazhong University of Science and Technology Union Shenzhen Hospital (the 6th Affiliated Hospital of Shenzhen University), Shenzhen 518052, P.R. China.
  • Xian Y; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, P.R. China.
  • Li Q; Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, P.R. China; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, P
  • Wu J; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, P.R. China; The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou 510120, P.R. China.
  • Ip S; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, P.R. China.
  • Xie Y; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, P.R. China.
  • Chen J; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, P.R. China.
  • Su Z; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, P.R. China.
  • Lin Z; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, P.R. China. Electronic address: linzx@cuhk.edu.hk.
  • Yang X; Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, P.R. China; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, P
Toxicology ; 451: 152680, 2021 03 15.
Article en En | MEDLINE | ID: mdl-33465425

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Especies Reactivas de Oxígeno / Carcinoma de Pulmón de Células no Pequeñas / Cuassinas / Factor 2 Relacionado con NF-E2 / Neoplasias Pulmonares / Mitocondrias / Antioxidantes Idioma: En Revista: Toxicology Año: 2021 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Especies Reactivas de Oxígeno / Carcinoma de Pulmón de Células no Pequeñas / Cuassinas / Factor 2 Relacionado con NF-E2 / Neoplasias Pulmonares / Mitocondrias / Antioxidantes Idioma: En Revista: Toxicology Año: 2021 Tipo del documento: Article