Linc-ROR promotes mesenchymal stem cells chondrogenesis and cartilage formation via regulating SOX9 expression.

Feng, L; Yang, Z M; Li, Y C; Wang, H X; Lo, J H T; Zhang, X T; Li, G

Feng, L; Yang, Z M; Li, Y C; Wang, H X; Lo, J H T; Zhang, X T; Li, G.

Afiliación

Feng L; Department of Orthopaedics & Traumatology, Stem Cells and Regenerative Medicine Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, SAR, PR China.
Yang ZM; Department of Orthopaedics & Traumatology, Stem Cells and Regenerative Medicine Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, SAR, PR China.
Li YC; Department of Orthopaedics & Traumatology, Stem Cells and Regenerative Medicine Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, SAR, PR China.
Wang HX; Department of Orthopaedics & Traumatology, Stem Cells and Regenerative Medicine Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, SAR, PR China.
Lo JHT; Department of Orthopaedics & Traumatology, Stem Cells and Regenerative Medicine Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, SAR, PR China.
Zhang XT; Department of Orthopaedics & Traumatology, Stem Cells and Regenerative Medicine Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, SAR, PR China.
Li G; Department of Orthopaedics & Traumatology, Stem Cells and Regenerative Medicine Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, SAR, PR China; MOE Key Laboratory for Regenerative Medicine, School of Biomedica

Osteoarthritis Cartilage ; 29(4): 568-578, 2021 04.

Article en En | MEDLINE | ID: mdl-33485931

Asunto(s)

Cartílago Articular/metabolismo; Condrogénesis/genética; Células Madre Mesenquimatosas/metabolismo; Osteoartritis de la Rodilla/genética; ARN Largo no Codificante/genética; Factor de Transcripción SOX9/genética; Anciano; Anciano de 80 o más Años; Agrecanos/metabolismo; Western Blotting; Colágeno Tipo X/metabolismo; Femenino; Humanos; Técnicas In Vitro; Masculino; Metaloproteinasa 13 de la Matriz/metabolismo; MicroARNs/metabolismo; Persona de Mediana Edad; Osteoartritis de la Rodilla/metabolismo; ARN Largo no Codificante/metabolismo; Reacción en Cadena en Tiempo Real de la Polimerasa; Factor de Transcripción SOX9/metabolismo; Regulación hacia Arriba

Palabras clave

BMSCs; Chondrogenesis; Hydrogels; Linc-ROR

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Cartílago Articular / Osteoartritis de la Rodilla / Condrogénesis / Factor de Transcripción SOX9 / Células Madre Mesenquimatosas / ARN Largo no Codificante Idioma: En Revista: Osteoarthritis Cartilage Asunto de la revista: ORTOPEDIA / REUMATOLOGIA Año: 2021 Tipo del documento: Article

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