Zika virus RNA excretion in sweat with concomitant detection in other body fluid specimens.
Mem Inst Oswaldo Cruz
; 115: e200339, 2021.
Article
en En
| MEDLINE
| ID: mdl-33503145
ABSTRACT
We evaluated sweat, blood and urine specimens obtained from an ongoing cohort study in Brazil. Samples were collected at pre-established intervals after the initial rash presentation and tested for Zika virus (ZIKV) RNA presence by real-time reverse transcriptase polymerase chain reaction (rRT-PCR). From 254 participants with confirmed infection, ZIKV RNA was detected in the sweat of 46 individuals (18.1%). Sweat presented a median cycle threshold (Ct) of 34.74 [interquartile range (IQR) 33.44-36.04], comparable to plasma (Ct 35.96 - IQR 33.29-36.69) and higher than urine (Ct 30.78 - IQR 28.72-33.22). Concomitant detection with other specimens was observed in 33 (72%) of 46 participants who had a positive result in sweat. These findings represent an unusual and not yet investigated virus shedding through eccrine glands.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Sudor
/
ARN Viral
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Virus Zika
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Infección por el Virus Zika
Tipo de estudio:
Diagnostic_studies
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Etiology_studies
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Incidence_studies
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Observational_studies
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Risk_factors_studies
País/Región como asunto:
America do sul
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Brasil
Idioma:
En
Revista:
Mem Inst Oswaldo Cruz
Año:
2021
Tipo del documento:
Article