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Mantle cell lymphomas with concomitant MYC and CCND1 breakpoints are recurrently TdT positive and frequently show high-grade pathological and genetic features.
Aukema, Sietse M; Croci, Giorgio A; Bens, Susanne; Oehl-Huber, Kathrin; Wagener, Rabea; Ott, German; Rosenwald, Andreas; Kluin, Philip M; van den Berg, Eva; Bosga-Bouwer, Anneke G; Hoogendoorn, Mels; Hoster, Eva; Bittmann, Iris; Nagel, Inga; Murga Penas, Eva M; Kreuz, Markus; Bausinger, Julia; Belder, Wilfried; Oschlies, Ilske; Dyer, Martin J S; Jayne, Sandrine; Siebert, Reiner; Klapper, Wolfram.
Afiliación
  • Aukema SM; Institute of Human Genetics, Christian-Albrechts University Kiel & University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany. smaukema@gmail.com.
  • Croci GA; Hematopathology Section, Christian-Albrechts-University, Kiel, Germany. smaukema@gmail.com.
  • Bens S; Hematopathology Section, Christian-Albrechts-University, Kiel, Germany.
  • Oehl-Huber K; Pathology Unit, Department of Pathophysiology and Transplantation, University of Milan and Fondazione IRCCS, Ca' Granda - Maggiore Policlinico, Milan, Italy.
  • Wagener R; Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany.
  • Ott G; Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany.
  • Rosenwald A; Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany.
  • Kluin PM; Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
  • van den Berg E; Department of Clinical Pathology, Robert-Bosch-Krankenhaus, and Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.
  • Bosga-Bouwer AG; Institute of Pathology, University of Würzburg, Würzburg, Germany.
  • Hoogendoorn M; Department of Pathology & Medical Biology, University Medical Center Groningen, Groningen, the Netherlands.
  • Hoster E; Department of Genetics, University Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
  • Bittmann I; Department of Genetics, University Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
  • Nagel I; Department of Internal Medicine, Medisch Centrum Leeuwarden, Leeuwarden, the Netherlands.
  • Murga Penas EM; Institute for Medical Information Processing, Biometry and Epidemiology (IBE), Ludwig-Maximilians-Universität Munich, Munich, Germany.
  • Kreuz M; Department of Medicine III, University Hospital of the Ludwig Maximilians University Munich, Munich, Germany.
  • Bausinger J; Institute of Pathology, Agaplesion Hospital Rotenburg, Rotenburg (Wuemme), Germany.
  • Belder W; Institute of Human Genetics, Christian-Albrechts University Kiel & University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Oschlies I; Institute of Experimental and Clinical Pharmacology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Dyer MJS; Institute of Human Genetics, Christian-Albrechts University Kiel & University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Jayne S; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
  • Siebert R; Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany.
  • Klapper W; Pathologie Gütersloh, Gütersloh, Germany.
Virchows Arch ; 479(1): 133-145, 2021 Jul.
Article en En | MEDLINE | ID: mdl-33528622

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Reordenamiento Génico / Biomarcadores de Tumor / Proteínas Proto-Oncogénicas c-myc / Ciclina D1 / Linfoma de Células del Manto / Puntos de Rotura del Cromosoma Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Virchows Arch Asunto de la revista: BIOLOGIA MOLECULAR / PATOLOGIA Año: 2021 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Reordenamiento Génico / Biomarcadores de Tumor / Proteínas Proto-Oncogénicas c-myc / Ciclina D1 / Linfoma de Células del Manto / Puntos de Rotura del Cromosoma Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Virchows Arch Asunto de la revista: BIOLOGIA MOLECULAR / PATOLOGIA Año: 2021 Tipo del documento: Article