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Integrating genome-wide CRISPR immune screen with multi-omic clinical data reveals distinct classes of tumor intrinsic immune regulators.
Hou, Jiakai; Wang, Yunfei; Shi, Leilei; Chen, Yuan; Xu, Chunyu; Saeedi, Arash; Pan, Ke; Bohat, Ritu; Egan, Nicholas A; McKenzie, Jodi A; Mbofung, Rina M; Williams, Leila J; Yang, Zhenhuang; Sun, Ming; Liang, Xiaofang; Rodon Ahnert, Jordi; Varadarajan, Navin; Yee, Cassian; Chen, Yiwen; Hwu, Patrick; Peng, Weiyi.
Afiliación
  • Hou J; Department of Biology and Biochemistry, University of Houston, Houston, Texas, USA.
  • Wang Y; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Shi L; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Chen Y; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Xu C; Department of Biology and Biochemistry, University of Houston, Houston, Texas, USA.
  • Saeedi A; Department of Chemical and Biomolecular Engineering, University of Houston, Houston, Texas, USA.
  • Pan K; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Bohat R; Department of Biology and Biochemistry, University of Houston, Houston, Texas, USA.
  • Egan NA; Department of Biology and Biochemistry, University of Houston, Houston, Texas, USA.
  • McKenzie JA; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Mbofung RM; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Williams LJ; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Yang Z; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Sun M; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Liang X; Department of Biology and Biochemistry, University of Houston, Houston, Texas, USA.
  • Rodon Ahnert J; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Varadarajan N; Department of Chemical and Biomolecular Engineering, University of Houston, Houston, Texas, USA.
  • Yee C; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Chen Y; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Hwu P; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA wpeng2@central.uh.edu patrick.hwu@moffitt.org ychen26@mdanderson.org.
  • Peng W; Department of Cutaneous Oncology, Moffitt Cancer Center, Tampa, Florida, USA wpeng2@central.uh.edu patrick.hwu@moffitt.org ychen26@mdanderson.org.
J Immunother Cancer ; 9(2)2021 02.
Article en En | MEDLINE | ID: mdl-33589527
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Escape del Tumor / Genómica / Microambiente Tumoral / Sistemas CRISPR-Cas / Neoplasias Tipo de estudio: Prognostic_studies Idioma: En Revista: J Immunother Cancer Año: 2021 Tipo del documento: Article
Texto completo
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PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Escape del Tumor / Genómica / Microambiente Tumoral / Sistemas CRISPR-Cas / Neoplasias Tipo de estudio: Prognostic_studies Idioma: En Revista: J Immunother Cancer Año: 2021 Tipo del documento: Article