Description of two fatal cases of melioidosis in Mexican children with acute pneumonia: case report.
BMC Infect Dis
; 21(1): 204, 2021 Feb 23.
Article
en En
| MEDLINE
| ID: mdl-33622263
ABSTRACT
BACKGROUND:
Melioidosis is an infectious disease caused by Burkholderia pseudomallei. In Mexico, the disease is rarely diagnosed in humans and there is no evidence of simultaneous environmental isolation of the pathogen. Here, we describe clinical profiles of fatal cases of melioidosis in two children, in a region without history of that disease. CASE PRESENTATION About 48 h before onset of symptoms, patients swam in a natural body of water, and thereafter they rapidly developed fatal septicemic illness. Upon necropsy, samples from liver, spleen, lung, cerebrospinal fluid, and bronchial aspirate tissues contained Burkholderia pseudomallei. Environmental samples collected from the locations where the children swam also contained B. pseudomallei. All the clinical and environmental strains showed the same BOX-PCR pattern, suggesting that infection originated from the area where the patients were swimming.CONCLUSIONS:
The identification of B. pseudomallei confirmed that melioidosis disease exists in Sonora, Mexico. The presence of B. pseudomallei in the environment may suggest endemicity of the pathogen in the region. This study highlights the importance of strengthening laboratory capacity to prevent and control future melioidosis cases.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Neumonía Bacteriana
/
Melioidosis
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
País/Región como asunto:
Mexico
Idioma:
En
Revista:
BMC Infect Dis
Asunto de la revista:
DOENCAS TRANSMISSIVEIS
Año:
2021
Tipo del documento:
Article