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Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion.
Frangieh, Chris J; Melms, Johannes C; Thakore, Pratiksha I; Geiger-Schuller, Kathryn R; Ho, Patricia; Luoma, Adrienne M; Cleary, Brian; Jerby-Arnon, Livnat; Malu, Shruti; Cuoco, Michael S; Zhao, Maryann; Ager, Casey R; Rogava, Meri; Hovey, Lila; Rotem, Asaf; Bernatchez, Chantale; Wucherpfennig, Kai W; Johnson, Bruce E; Rozenblatt-Rosen, Orit; Schadendorf, Dirk; Regev, Aviv; Izar, Benjamin.
Afiliación
  • Frangieh CJ; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Melms JC; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Thakore PI; Columbia Center for Translational Immunology, New York, NY, USA.
  • Geiger-Schuller KR; Department of Medicine, Division of Hematology and Oncology, Columbia University Medical Center, New York, NY, USA.
  • Ho P; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Luoma AM; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Cleary B; Genentech, South San Francisco, CA, USA.
  • Jerby-Arnon L; Columbia Center for Translational Immunology, New York, NY, USA.
  • Malu S; Department of Medicine, Division of Hematology and Oncology, Columbia University Medical Center, New York, NY, USA.
  • Cuoco MS; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Zhao M; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Ager CR; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Rogava M; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Hovey L; Chan Zuckerberg Biohub, San Francisco, CA, USA.
  • Rotem A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Bernatchez C; Immunitas Therapeutics, Waltham, MA, USA.
  • Wucherpfennig KW; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Johnson BE; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Rozenblatt-Rosen O; Columbia Center for Translational Immunology, New York, NY, USA.
  • Schadendorf D; Columbia Center for Translational Immunology, New York, NY, USA.
  • Regev A; Department of Medicine, Division of Hematology and Oncology, Columbia University Medical Center, New York, NY, USA.
  • Izar B; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Nat Genet ; 53(3): 332-341, 2021 03.
Article en En | MEDLINE | ID: mdl-33649592

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Escape del Tumor / Resistencia a Antineoplásicos / Antígenos CD58 / Análisis de la Célula Individual / Melanoma Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2021 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Escape del Tumor / Resistencia a Antineoplásicos / Antígenos CD58 / Análisis de la Célula Individual / Melanoma Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2021 Tipo del documento: Article