The methyltransferase SETD2 couples transcription and splicing by engaging mRNA processing factors through its SHI domain.

Bhattacharya, Saikat; Levy, Michaella J; Zhang, Ning; Li, Hua; Florens, Laurence; Washburn, Michael P; Workman, Jerry L

Bhattacharya, Saikat; Levy, Michaella J; Zhang, Ning; Li, Hua; Florens, Laurence; Washburn, Michael P; Workman, Jerry L.

Afiliación

Bhattacharya S; Stowers Institute for Medical Research, Kansas City, MO, USA.
Levy MJ; Stowers Institute for Medical Research, Kansas City, MO, USA.
Zhang N; Stowers Institute for Medical Research, Kansas City, MO, USA.
Li H; Stowers Institute for Medical Research, Kansas City, MO, USA.
Florens L; Stowers Institute for Medical Research, Kansas City, MO, USA.
Washburn MP; Department of Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA.
Workman JL; Stowers Institute for Medical Research, Kansas City, MO, USA. jlw@stowers.org.

Nat Commun ; 12(1): 1443, 2021 03 04.

Article en En | MEDLINE | ID: mdl-33664260

Asunto(s)

Empalme Alternativo/genética; Ribonucleoproteína Heterogénea-Nuclear Grupo L/metabolismo; N-Metiltransferasa de Histona-Lisina/metabolismo; Precursores del ARN/genética; ARN Mensajero/genética; Línea Celular; Células HEK293; N-Metiltransferasa de Histona-Lisina/genética; Histonas/metabolismo; Humanos; Dominios Proteicos/fisiología; ARN Polimerasa II/metabolismo

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: ARN Mensajero / Precursores del ARN / N-Metiltransferasa de Histona-Lisina / Empalme Alternativo / Ribonucleoproteína Heterogénea-Nuclear Grupo L Tipo de estudio: Prognostic_studies Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article

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