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Trajectories of Symptom Severity in Children with Autism: Variability and Turning Points through the Transition to School.
Georgiades, Stelios; Tait, Peter A; McNicholas, Paul D; Duku, Eric; Zwaigenbaum, Lonnie; Smith, Isabel M; Bennett, Teresa; Elsabbagh, Mayada; Kerns, Connor M; Mirenda, Pat; Ungar, Wendy J; Vaillancourt, Tracy; Volden, Joanne; Waddell, Charlotte; Zaidman-Zait, Anat; Gentles, Stephen; Szatmari, Peter.
Afiliación
  • Georgiades S; Department of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main St. W. - MIP Suite 201A, Hamilton, ON, L8S 4K1, Canada. georgis@mcmaster.ca.
  • Tait PA; Department of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main St. W. - MIP Suite 201A, Hamilton, ON, L8S 4K1, Canada.
  • McNicholas PD; Department of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main St. W. - MIP Suite 201A, Hamilton, ON, L8S 4K1, Canada.
  • Duku E; Department of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main St. W. - MIP Suite 201A, Hamilton, ON, L8S 4K1, Canada.
  • Zwaigenbaum L; University of Alberta, Edmonton, Canada.
  • Smith IM; IWK Health Centre, Dalhousie University, Halifax, Canada.
  • Bennett T; Department of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main St. W. - MIP Suite 201A, Hamilton, ON, L8S 4K1, Canada.
  • Elsabbagh M; McGill University, Montreal, Canada.
  • Kerns CM; University of British Columbia, Vancouver, Canada.
  • Mirenda P; University of British Columbia, Vancouver, Canada.
  • Ungar WJ; University of Toronto, The Hospital for Sick Children, Toronto, Canada.
  • Vaillancourt T; University of Ottawa, Ottawa, Canada.
  • Volden J; University of Alberta, Edmonton, Canada.
  • Waddell C; Simon Fraser University, Burnaby, Canada.
  • Zaidman-Zait A; Tel Aviv University, Tel Aviv, Israel.
  • Gentles S; Department of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main St. W. - MIP Suite 201A, Hamilton, ON, L8S 4K1, Canada.
  • Szatmari P; Centre for Addition and Mental Health, Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, The Hospital for Sick Children, Toronto, Canada.
J Autism Dev Disord ; 52(1): 392-401, 2022 Jan.
Article en En | MEDLINE | ID: mdl-33704613
ABSTRACT
This study examined the trajectories of autistic symptom severity in an inception cohort of 187 children with ASD assessed across four time points from diagnosis to age 10. Trajectory groups were derived using multivariate cluster analysis. A two trajectory/cluster solution was selected. Change in trajectory slopes revealed a turning point marked by plateauing in symptom reduction during the period of transition to school (age 6) for one of the two trajectories. Trajectories were labelled Continuously Improving (27%) and Improving then Plateauing (73% of sample). Children in the two trajectories differed in levels of symptom severity, language, cognitive, and adaptive functioning skills. Study findings can inform the development of more personalized services for children with ASD transitioning into the school system.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Trastorno Autístico / Trastorno del Espectro Autista Tipo de estudio: Diagnostic_studies Idioma: En Revista: J Autism Dev Disord Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Trastorno Autístico / Trastorno del Espectro Autista Tipo de estudio: Diagnostic_studies Idioma: En Revista: J Autism Dev Disord Año: 2022 Tipo del documento: Article