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Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin.
Carnero Corrales, Marjorie A; Zinken, Sarah; Konstantinidis, Georgios; Rafehi, Muhammad; Abdelrahman, Aliaa; Wu, Yao-Wen; Janning, Petra; Müller, Christa E; Laraia, Luca; Waldmann, Herbert.
Afiliación
  • Carnero Corrales MA; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Straße 11, 44227 Dortmund, Germany; Technische Universität Dortmund, Faculty of Chemistry and Chemical Biology, Otto-Hahn-Straße 6, 44227 Dortmund, Germany.
  • Zinken S; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Straße 11, 44227 Dortmund, Germany; Technische Universität Dortmund, Faculty of Chemistry and Chemical Biology, Otto-Hahn-Straße 6, 44227 Dortmund, Germany.
  • Konstantinidis G; Chemical Genomics Center of the Max Planck Society, Otto-Hahn-Straße 15, 44227 Dortmund, Germany; Department of Chemistry, Umeå University, 90187 Umeå, Sweden.
  • Rafehi M; PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Sciences Bonn (PSB), Pharmaceutical Chemistry I, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany.
  • Abdelrahman A; PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Sciences Bonn (PSB), Pharmaceutical Chemistry I, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany.
  • Wu YW; Chemical Genomics Center of the Max Planck Society, Otto-Hahn-Straße 15, 44227 Dortmund, Germany; Department of Chemistry, Umeå University, 90187 Umeå, Sweden.
  • Janning P; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Straße 11, 44227 Dortmund, Germany; Technische Universität Dortmund, Faculty of Chemistry and Chemical Biology, Otto-Hahn-Straße 6, 44227 Dortmund, Germany.
  • Müller CE; PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Sciences Bonn (PSB), Pharmaceutical Chemistry I, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany.
  • Laraia L; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Straße 11, 44227 Dortmund, Germany; Department of Chemistry, Technical University of Denmark, Kemitorvet 207, Room 124, 2800 Kongens Lyngby, Denmark. Electronic address: luclar@kemi.dtu.dk.
  • Waldmann H; Max Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Straße 11, 44227 Dortmund, Germany; Technische Universität Dortmund, Faculty of Chemistry and Chemical Biology, Otto-Hahn-Straße 6, 44227 Dortmund, Germany. Electronic address: herbert.waldmann@mpi-dortmund.mpg.d
Cell Chem Biol ; 28(12): 1750-1757.e5, 2021 12 16.
Article en En | MEDLINE | ID: mdl-33725479
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Autofagia / Temperatura / Proteoma / Receptores Purinérgicos P2X4 / Antagonistas del Receptor Purinérgico P2X Idioma: En Revista: Cell Chem Biol Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Autofagia / Temperatura / Proteoma / Receptores Purinérgicos P2X4 / Antagonistas del Receptor Purinérgico P2X Idioma: En Revista: Cell Chem Biol Año: 2021 Tipo del documento: Article