Driving to Safety: CRISPR-Based Genetic Approaches to Reducing Antibiotic Resistance.

Bier, Ethan; Nizet, Victor

Bier, Ethan; Nizet, Victor.

Afiliación

Bier E; Tata Institute for Genetics and Society, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0349, USA; Section of Cell and Developmental Biology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0349, USA. Electronic address: ebier@ucsd.edu.
Nizet V; Tata Institute for Genetics and Society, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0349, USA; Collaborative to Halt Antibiotic-Resistant Microbes, Department of Pediatrics, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0687, USA; Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0687, USA.

Trends Genet ; 37(8): 745-757, 2021 08.

Article en En | MEDLINE | ID: mdl-33745750

Asunto(s)

Antibacterianos/uso terapéutico; Sistemas CRISPR-Cas/genética; Farmacorresistencia Microbiana/genética; Genoma Bacteriano/genética; Antibacterianos/efectos adversos; Edición Génica/métodos; Genoma Bacteriano/efectos de los fármacos; Humanos

Palabras clave

CRISPR; Cas9; active genetics; antibiotic resistance; antimicrobial; bacteria; conjugation; gene drive; genome editing; horizontal gene transfer; phage; pro-AG; proactive genetics; transposon

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Farmacorresistencia Microbiana / Genoma Bacteriano / Sistemas CRISPR-Cas / Antibacterianos Idioma: En Revista: Trends Genet Asunto de la revista: GENETICA Año: 2021 Tipo del documento: Article

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