O-GlcNAcylation promotes the migratory ability of hepatocellular carcinoma cells via regulating FOXA2 stability and transcriptional activity.

Huang, Huang; Wu, Qiong; Guo, Xinyi; Huang, Tianmiao; Xie, Xueqin; Wang, Lingyan; Liu, Yangzhi; Shi, Lin; Li, Wenli; Zhang, Jianing; Liu, Yubo

Huang, Huang; Wu, Qiong; Guo, Xinyi; Huang, Tianmiao; Xie, Xueqin; Wang, Lingyan; Liu, Yangzhi; Shi, Lin; Li, Wenli; Zhang, Jianing; Liu, Yubo.

Afiliación

Huang H; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Wu Q; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Guo X; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Huang T; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Xie X; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Wang L; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Liu Y; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Shi L; The Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Li W; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Zhang J; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Liu Y; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.

J Cell Physiol ; 236(11): 7491-7503, 2021 11.

Article en En | MEDLINE | ID: mdl-33843053

Asunto(s)

Carcinoma Hepatocelular/metabolismo; Factor Nuclear 3-beta del Hepatocito/metabolismo; Neoplasias Hepáticas/metabolismo; Procesamiento Proteico-Postraduccional; Transcripción Genética; Antígenos CD/genética; Antígenos CD/metabolismo; Cadherinas/genética; Cadherinas/metabolismo; Carcinoma Hepatocelular/genética; Carcinoma Hepatocelular/secundario; Movimiento Celular; Regulación Neoplásica de la Expresión Génica; Glicosilación; Células HEK293; Células Hep G2; Factor Nuclear 3-beta del Hepatocito/genética; Humanos; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/patología; N-Acetilglucosaminiltransferasas/genética; N-Acetilglucosaminiltransferasas/metabolismo; Invasividad Neoplásica; Estabilidad Proteica; Proteolisis; Ubiquitinación

Palabras clave

E-cadherin; FOXA2; O-GlcNAcylation; hepatocellular carcinoma; metastasis

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Transcripción Genética / Procesamiento Proteico-Postraduccional / Carcinoma Hepatocelular / Factor Nuclear 3-beta del Hepatocito / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies Idioma: En Revista: J Cell Physiol Año: 2021 Tipo del documento: Article

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