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Structure-Guided Design of G-Protein-Coupled Receptor Polypharmacology.
Kampen, Stefanie; Duy Vo, Duc; Zhang, Xiaoqun; Panel, Nicolas; Yang, Yunting; Jaiteh, Mariama; Matricon, Pierre; Svenningsson, Per; Brea, Jose; Loza, Maria Isabel; Kihlberg, Jan; Carlsson, Jens.
Afiliación
  • Kampen S; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, 75124, Uppsala, Sweden.
  • Duy Vo D; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, 75124, Uppsala, Sweden.
  • Zhang X; Department of Clinical Neuroscience, Karolinska Institute, 17177, Stockholm, Sweden.
  • Panel N; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, 75124, Uppsala, Sweden.
  • Yang Y; Department of Clinical Neuroscience, Karolinska Institute, 17177, Stockholm, Sweden.
  • Jaiteh M; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, 75124, Uppsala, Sweden.
  • Matricon P; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, 75124, Uppsala, Sweden.
  • Svenningsson P; Department of Clinical Neuroscience, Karolinska Institute, 17177, Stockholm, Sweden.
  • Brea J; USEF Screening Platform-BioFarma Research Group, Centre for Research in Molecular Medicine and Chronic Diseases, University of Santiago de Compostela, 15706, Santiago, de Compostela, Spain.
  • Loza MI; USEF Screening Platform-BioFarma Research Group, Centre for Research in Molecular Medicine and Chronic Diseases, University of Santiago de Compostela, 15706, Santiago, de Compostela, Spain.
  • Kihlberg J; Department of Chemistry-BMC, Uppsala University, 75123, Uppsala, Sweden.
  • Carlsson J; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, 75124, Uppsala, Sweden.
Angew Chem Int Ed Engl ; 60(33): 18022-18030, 2021 08 09.
Article en En | MEDLINE | ID: mdl-33904641
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Receptores de Dopamina D2 / Receptor de Adenosina A2A / Bibliotecas de Moléculas Pequeñas / Antiparkinsonianos Tipo de estudio: Prognostic_studies Idioma: En Revista: Angew Chem Int Ed Engl Año: 2021 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Receptores de Dopamina D2 / Receptor de Adenosina A2A / Bibliotecas de Moléculas Pequeñas / Antiparkinsonianos Tipo de estudio: Prognostic_studies Idioma: En Revista: Angew Chem Int Ed Engl Año: 2021 Tipo del documento: Article