Amoeba Predation of Cryptococcus neoformans Results in Pleiotropic Changes to Traits Associated with Virulence.

Fu, Man Shun; Liporagi-Lopes, Livia C; Dos Santos, Samuel R; Tenor, Jennifer L; Perfect, John R; Cuomo, Christina A; Casadevall, Arturo

Fu, Man Shun; Liporagi-Lopes, Livia C; Dos Santos, Samuel R; Tenor, Jennifer L; Perfect, John R; Cuomo, Christina A; Casadevall, Arturo.

Afiliación

Fu MS; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Liporagi-Lopes LC; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Dos Santos SR; Departamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Tenor JL; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Perfect JR; Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
Cuomo CA; Division of Infectious Diseases, Department of Medicine and Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.
Casadevall A; Division of Infectious Diseases, Department of Medicine and Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.

mBio ; 12(2)2021 04 27.

Article en En | MEDLINE | ID: mdl-33906924

Asunto(s)

Acanthamoeba castellanii/fisiología; Criptococosis/microbiología; Cryptococcus neoformans/patogenicidad; Fagocitosis; Acanthamoeba castellanii/microbiología; Animales; Criptococosis/inmunología; Cryptococcus neoformans/clasificación; Cryptococcus neoformans/genética; Citocinas/inmunología; Femenino; Humanos; Larva/microbiología; Macrófagos/microbiología; Ratones Endogámicos C57BL; Mariposas Nocturnas/microbiología; Fagocitos/microbiología; Fenotipo; Virulencia

Palabras clave

Acanthamoeba castellanii; Cryptococcus neoformans; amoeba; evolution; host-pathogen interactions; macrophages; opportunistic fungi

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Fagocitosis / Criptococosis / Cryptococcus neoformans / Acanthamoeba castellanii Tipo de estudio: Risk_factors_studies Idioma: En Revista: MBio Año: 2021 Tipo del documento: Article

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