Expression of serum response factor in the lung mesenchyme is essential for development of pulmonary fibrosis.

Bernau, Ksenija; Leet, Jonathan Paul; Bruhn, Ellen Marie; Tubbs, Austin James; Zhu, Terry; Sandbo, Nathan

Bernau, Ksenija; Leet, Jonathan Paul; Bruhn, Ellen Marie; Tubbs, Austin James; Zhu, Terry; Sandbo, Nathan.

Afiliación

Bernau K; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin.
Leet JP; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin.
Bruhn EM; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin.
Tubbs AJ; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin.
Zhu T; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin.
Sandbo N; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin.

Am J Physiol Lung Cell Mol Physiol ; 321(1): L174-L188, 2021 07 01.

Article en En | MEDLINE | ID: mdl-33978489

Asunto(s)

Bleomicina/toxicidad; Diferenciación Celular; Pulmón/patología; Mesodermo/patología; Fibrosis Pulmonar/patología; Factor de Respuesta Sérica/metabolismo; Animales; Antibióticos Antineoplásicos/toxicidad; Estudios de Casos y Controles; Matriz Extracelular/efectos de los fármacos; Matriz Extracelular/metabolismo; Matriz Extracelular/patología; Femenino; Regulación de la Expresión Génica; Humanos; Pulmón/efectos de los fármacos; Pulmón/metabolismo; Masculino; Mesodermo/metabolismo; Ratones; Ratones Endogámicos C57BL; Fibrosis Pulmonar/etiología; Fibrosis Pulmonar/metabolismo; Factor de Respuesta Sérica/genética

Palabras clave

SRF; Tbx4; fibroblast; lung mesenchymal cell; pulmonary fibrosis

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Fibrosis Pulmonar / Bleomicina / Diferenciación Celular / Factor de Respuesta Sérica / Pulmón / Mesodermo Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Idioma: En Revista: Am J Physiol Lung Cell Mol Physiol Asunto de la revista: BIOLOGIA MOLECULAR / FISIOLOGIA Año: 2021 Tipo del documento: Article

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