Interferon Î³ neutralization reduces blood pressure, uterine artery resistance index, and placental oxidative stress in placental ischemic rats.

Travis, Olivia K; Tardo, Geilda A; Giachelli, Chelsea; Siddiq, Shani; Nguyen, Henry T; Crosby, Madison T; Johnson, Tyler D; Brown, Andrea K; Booz, George W; Smith, Alex N; Williams, Jan Michael; Cornelius, Denise C

Travis, Olivia K; Tardo, Geilda A; Giachelli, Chelsea; Siddiq, Shani; Nguyen, Henry T; Crosby, Madison T; Johnson, Tyler D; Brown, Andrea K; Booz, George W; Smith, Alex N; Williams, Jan Michael; Cornelius, Denise C.

Afiliación

Travis OK; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Tardo GA; Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
Giachelli C; Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
Siddiq S; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Nguyen HT; Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
Crosby MT; Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
Johnson TD; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Brown AK; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Booz GW; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Smith AN; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Williams JM; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.
Cornelius DC; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi.

Am J Physiol Regul Integr Comp Physiol ; 321(2): R112-R124, 2021 08 01.

Article en En | MEDLINE | ID: mdl-34075808

Asunto(s)

Anticuerpos Monoclonales/farmacología; Presión Arterial/efectos de los fármacos; Interferón gamma/antagonistas & inhibidores; Células Asesinas Naturales/efectos de los fármacos; Estrés Oxidativo/efectos de los fármacos; Placenta/irrigación sanguínea; Placenta/efectos de los fármacos; Preeclampsia/prevención & control; Arteria Uterina/efectos de los fármacos; Resistencia Vascular/efectos de los fármacos; Proteínas Angiogénicas/metabolismo; Animales; Modelos Animales de Enfermedad; Femenino; Retardo del Crecimiento Fetal/metabolismo; Retardo del Crecimiento Fetal/fisiopatología; Retardo del Crecimiento Fetal/prevención & control; Interferón gamma/metabolismo; Isquemia/metabolismo; Isquemia/fisiopatología; Células Asesinas Naturales/metabolismo; Placenta/metabolismo; Circulación Placentaria; Preeclampsia/metabolismo; Preeclampsia/fisiopatología; Embarazo; Ratas Sprague-Dawley; Especies Reactivas de Oxígeno/metabolismo; Arteria Uterina/metabolismo; Arteria Uterina/fisiopatología

Palabras clave

interferon Î³; preeclampsia; reactive oxygen species; soluble Fms-like tyrosine kinase-1

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Placenta / Preeclampsia / Resistencia Vascular / Células Asesinas Naturales / Interferón gamma / Estrés Oxidativo / Arteria Uterina / Presión Arterial / Anticuerpos Monoclonales Idioma: En Revista: Am J Physiol Regul Integr Comp Physiol Asunto de la revista: FISIOLOGIA Año: 2021 Tipo del documento: Article

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