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Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites.
Hosseinzadeh, Parisa; Watson, Paris R; Craven, Timothy W; Li, Xinting; Rettie, Stephen; Pardo-Avila, Fátima; Bera, Asim K; Mulligan, Vikram Khipple; Lu, Peilong; Ford, Alexander S; Weitzner, Brian D; Stewart, Lance J; Moyer, Adam P; Di Piazza, Maddalena; Whalen, Joshua G; Greisen, Per Jr; Christianson, David W; Baker, David.
Afiliación
  • Hosseinzadeh P; University of Washington, Department of Biochemistry, Institute for Protein Design, Seattle, WA, USA.
  • Watson PR; Knight Campus Center, University of Oregon, Eugene, OR, USA.
  • Craven TW; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA.
  • Li X; University of Washington, Department of Biochemistry, Institute for Protein Design, Seattle, WA, USA.
  • Rettie S; University of Washington, Department of Biochemistry, Institute for Protein Design, Seattle, WA, USA.
  • Pardo-Avila F; University of Washington, Department of Biochemistry, Institute for Protein Design, Seattle, WA, USA.
  • Bera AK; Molecular and Cellular Biology Ph.D. Program, University of Washington, Seattle, WA, USA.
  • Mulligan VK; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
  • Lu P; University of Washington, Department of Biochemistry, Institute for Protein Design, Seattle, WA, USA.
  • Ford AS; University of Washington, Department of Biochemistry, Institute for Protein Design, Seattle, WA, USA.
  • Weitzner BD; Systems Biology, Center for Computational Biology, Flatiron Institute, New York, NY, USA.
  • Stewart LJ; University of Washington, Department of Biochemistry, Institute for Protein Design, Seattle, WA, USA.
  • Moyer AP; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province, China.
  • Di Piazza M; University of Washington, Department of Biochemistry, Institute for Protein Design, Seattle, WA, USA.
  • Whalen JG; University of Washington, Department of Biochemistry, Institute for Protein Design, Seattle, WA, USA.
  • Greisen PJ; Lyell Immunopharma, Inc., Seattle, WA, USA.
  • Christianson DW; University of Washington, Department of Biochemistry, Institute for Protein Design, Seattle, WA, USA.
  • Baker D; University of Washington, Department of Biochemistry, Institute for Protein Design, Seattle, WA, USA.
Nat Commun ; 12(1): 3384, 2021 06 07.
Article en En | MEDLINE | ID: mdl-34099674
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Péptidos Cíclicos / Relación Estructura-Actividad / Diseño de Fármacos / Inhibidores de Histona Desacetilasas Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Péptidos Cíclicos / Relación Estructura-Actividad / Diseño de Fármacos / Inhibidores de Histona Desacetilasas Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article