Integrative analyses identified ion channel genes GJB2 and SCNN1B as prognostic biomarkers and therapeutic targets for lung adenocarcinoma.

Lu, Ao; Shi, Yidan; Liu, Yijuan; Lin, Jiahao; Zhang, Huarong; Guo, Yating; Li, Lisheng; Lin, Zeman; Wu, Junling; Ji, Daihan; Wang, Chengdang

Lu, Ao; Shi, Yidan; Liu, Yijuan; Lin, Jiahao; Zhang, Huarong; Guo, Yating; Li, Lisheng; Lin, Zeman; Wu, Junling; Ji, Daihan; Wang, Chengdang.

Afiliación

Lu A; Department of Gastroenterology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350122, China; Department of Bioinformatics, Fujian Key Laboratory of Medical Bioinformatics, School of Medical Technology and Engineering, Fujian Medical University, Fuzhou, China. Electronic address
Shi Y; Department of Bioinformatics, Fujian Key Laboratory of Medical Bioinformatics, School of Medical Technology and Engineering, Fujian Medical University, Fuzhou, China.
Liu Y; Department of Gastroenterology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350122, China.
Lin J; Department of Bioinformatics, Fujian Key Laboratory of Medical Bioinformatics, School of Medical Technology and Engineering, Fujian Medical University, Fuzhou, China.
Zhang H; Department of Bioinformatics, Fujian Key Laboratory of Medical Bioinformatics, School of Medical Technology and Engineering, Fujian Medical University, Fuzhou, China.
Guo Y; Department of Bioinformatics, Fujian Key Laboratory of Medical Bioinformatics, School of Medical Technology and Engineering, Fujian Medical University, Fuzhou, China.
Li L; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China.
Lin Z; Department of Bioinformatics, Fujian Key Laboratory of Medical Bioinformatics, School of Medical Technology and Engineering, Fujian Medical University, Fuzhou, China.
Wu J; Department of Bioinformatics, Fujian Key Laboratory of Medical Bioinformatics, School of Medical Technology and Engineering, Fujian Medical University, Fuzhou, China.
Ji D; Department of Bioinformatics, Fujian Key Laboratory of Medical Bioinformatics, School of Medical Technology and Engineering, Fujian Medical University, Fuzhou, China.
Wang C; Department of Gastroenterology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350122, China. Electronic address: wangcdhl@fjmu.edu.cn.

Lung Cancer ; 158: 29-39, 2021 08.

Article en En | MEDLINE | ID: mdl-34111567

Asunto(s)

Adenocarcinoma del Pulmón; Conexina 26/genética; Canales Epiteliales de Sodio/genética; Neoplasias Pulmonares; Adenocarcinoma del Pulmón/tratamiento farmacológico; Adenocarcinoma del Pulmón/genética; Biomarcadores de Tumor/genética; Regulación Neoplásica de la Expresión Génica; Humanos; Canales Iónicos/genética; Neoplasias Pulmonares/tratamiento farmacológico; Neoplasias Pulmonares/genética; Pronóstico

Palabras clave

Gene expression; Ion channel genes; Lung adenocarcinoma; Multi-omics analysis; Prognostic model

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Canales Epiteliales de Sodio / Conexina 26 / Adenocarcinoma del Pulmón / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Idioma: En Revista: Lung Cancer Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article

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