Exogenous ketone ester delays CNS oxygen toxicity without impairing cognitive and motor performance in male Sprague-Dawley rats.

Stavitzski, Nicole M; Landon, Carol S; Hinojo, Christopher M; Poff, Angela M; Rogers, Christopher Q; D'Agostino, Dominic P; Dean, Jay B

Stavitzski, Nicole M; Landon, Carol S; Hinojo, Christopher M; Poff, Angela M; Rogers, Christopher Q; D'Agostino, Dominic P; Dean, Jay B.

Afiliación

Stavitzski NM; Department of Molecular Pharmacology and Physiology, Hyperbaric Biomedical Research Laboratory, Morsani College of Medicine, University of South Florida, Tampa, Florida.
Landon CS; Department of Molecular Pharmacology and Physiology, Hyperbaric Biomedical Research Laboratory, Morsani College of Medicine, University of South Florida, Tampa, Florida.
Hinojo CM; Department of Molecular Pharmacology and Physiology, Hyperbaric Biomedical Research Laboratory, Morsani College of Medicine, University of South Florida, Tampa, Florida.
Poff AM; Department of Molecular Pharmacology and Physiology, Hyperbaric Biomedical Research Laboratory, Morsani College of Medicine, University of South Florida, Tampa, Florida.
Rogers CQ; Department of Molecular Pharmacology and Physiology, Hyperbaric Biomedical Research Laboratory, Morsani College of Medicine, University of South Florida, Tampa, Florida.
D'Agostino DP; Department of Molecular Pharmacology and Physiology, Hyperbaric Biomedical Research Laboratory, Morsani College of Medicine, University of South Florida, Tampa, Florida.
Dean JB; Institute of Human Machine and Cognition, Ocala, Florida.

Am J Physiol Regul Integr Comp Physiol ; 321(2): R100-R111, 2021 08 01.

Article en En | MEDLINE | ID: mdl-34132115

Asunto(s)

Anticonvulsivantes/farmacología; Conducta Animal/efectos de los fármacos; Encéfalo/efectos de los fármacos; Cognición/efectos de los fármacos; Ésteres/farmacología; Cetonas/farmacología; Actividad Motora/efectos de los fármacos; Convulsiones/prevención & control; Animales; Anticonvulsivantes/farmacocinética; Anticonvulsivantes/toxicidad; Encéfalo/fisiopatología; Modelos Animales de Enfermedad; Ésteres/farmacocinética; Ésteres/toxicidad; Oxigenoterapia Hiperbárica/efectos adversos; Cetonas/farmacocinética; Cetonas/toxicidad; Masculino; Ratas Sprague-Dawley; Tiempo de Reacción; Convulsiones/etiología; Convulsiones/fisiopatología; Convulsiones/psicología

Palabras clave

behavior; hyperbaric oxygen; ketone ester; oxygen toxicity; seizure

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Convulsiones / Conducta Animal / Encéfalo / Cognición / Ésteres / Cetonas / Actividad Motora / Anticonvulsivantes Tipo de estudio: Etiology_studies Idioma: En Revista: Am J Physiol Regul Integr Comp Physiol Asunto de la revista: FISIOLOGIA Año: 2021 Tipo del documento: Article

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