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Phase I First-in-Human Dose Escalation Study of the oral SF3B1 modulator H3B-8800 in myeloid neoplasms.
Steensma, David P; Wermke, Martin; Klimek, Virginia M; Greenberg, Peter L; Font, Patricia; Komrokji, Rami S; Yang, Jay; Brunner, Andrew M; Carraway, Hetty E; Ades, Lionel; Al-Kali, Aref; Alonso-Dominguez, Juan M; Alfonso-Piérola, Ana; Coombs, Catherine C; Deeg, H Joachim; Flinn, Ian; Foran, James M; Garcia-Manero, Guillermo; Maris, Michael B; McMasters, Malgorzata; Micol, Jean-Baptiste; De Oteyza, Jaime Perez; Thol, Felicitas; Wang, Eunice S; Watts, Justin M; Taylor, Justin; Stone, Richard; Gourineni, Vikram; Marino, Alyssa J; Yao, Huilan; Destenaves, Benoit; Yuan, Xiaobin; Yu, Kun; Dar, Sara; Ohanjanian, Lernik; Kuida, Keisuke; Xiao, Jianjun; Scholz, Catherine; Gualberto, Antonio; Platzbecker, Uwe.
Afiliación
  • Steensma DP; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Wermke M; University Hospital Dresden, Dresden, Germany.
  • Klimek VM; Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Greenberg PL; Stanford University Medical Center, Stanford, CA, USA.
  • Font P; Hospital General Universitario Gregorio Marañon, Madrid, Spain.
  • Komrokji RS; H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
  • Yang J; Karmanos Cancer Institute, Detroit, MI, USA.
  • Brunner AM; Massachusetts General Hospital, Boston, MA, USA.
  • Carraway HE; Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Ades L; Hopital Saint Louis, Paris, France.
  • Al-Kali A; Mayo Clinic, Rochester, MN, USA.
  • Alonso-Dominguez JM; Hospital Universitario Fundacion Jimenez Diaz- IISFJD-UAM, Madrid, Spain.
  • Alfonso-Piérola A; Clinica Universidad Navarra, Pamplona, Spain.
  • Coombs CC; University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Deeg HJ; Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Flinn I; Tennessee Oncology/Sarah Cannon Research Institute, Nashville, TN, USA.
  • Foran JM; Mayo Clinic, Jacksonville, FL, USA.
  • Garcia-Manero G; University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Maris MB; Colorado Blood Cancer Institute, Denver, CO, USA.
  • McMasters M; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Micol JB; Gustave Roussy Cancer Center, Villejuif, France.
  • De Oteyza JP; Hospital Universitario Sanchinarro, Madrid, Spain.
  • Thol F; Hannover Medical School, Hannover, Germany.
  • Wang ES; Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
  • Watts JM; University of Miami, Sylvester Comprehensive Cancer Center, Miami, FL, USA.
  • Taylor J; University of Miami, Sylvester Comprehensive Cancer Center, Miami, FL, USA.
  • Stone R; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Gourineni V; H3 Biomedicine, Cambridge, MA, USA.
  • Marino AJ; H3 Biomedicine, Cambridge, MA, USA.
  • Yao H; H3 Biomedicine, Cambridge, MA, USA.
  • Destenaves B; H3 Biomedicine, Cambridge, MA, USA.
  • Yuan X; Eisai, Inc, Woodcliff Lake, NJ, USA.
  • Yu K; H3 Biomedicine, Cambridge, MA, USA.
  • Dar S; H3 Biomedicine, Cambridge, MA, USA.
  • Ohanjanian L; H3 Biomedicine, Cambridge, MA, USA.
  • Kuida K; H3 Biomedicine, Cambridge, MA, USA.
  • Xiao J; H3 Biomedicine, Cambridge, MA, USA.
  • Scholz C; H3 Biomedicine, Cambridge, MA, USA.
  • Gualberto A; H3 Biomedicine, Cambridge, MA, USA. antonio_gualberto@h3biomedicine.com.
  • Platzbecker U; University Hospital Leipzig, Clinic for Hematology, Cellular Therapy and Hemostaseology, Leipzig, Germany. uwe.platzbecker@medizin.uni-leipzig.de.
Leukemia ; 35(12): 3542-3550, 2021 12.
Article en En | MEDLINE | ID: mdl-34172893
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Fosfoproteínas / Piperazinas / Piridinas / Síndromes Mielodisplásicos / Leucemia Mieloide Aguda / Factores de Empalme de ARN Tipo de estudio: Clinical_trials Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2021 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Fosfoproteínas / Piperazinas / Piridinas / Síndromes Mielodisplásicos / Leucemia Mieloide Aguda / Factores de Empalme de ARN Tipo de estudio: Clinical_trials Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2021 Tipo del documento: Article