Evaluation of the Gastroprotective Effect of the Flavonoid Complex from Lychnis chalcedonica L. on the Models of Experimental Ulcerogenesis.
Bull Exp Biol Med
; 171(2): 212-217, 2021 May.
Article
en En
| MEDLINE
| ID: mdl-34173095
ABSTRACT
Using rat and mouse models of neurogenic, ethanol-induced, and indometacin-induced damage to the gastric mucosa we demonstrated that course preventive treatment with flavonoid complex from aerial parts of Lychnis chalcedonica L. increased the resistance of gastric mucosa to ulcerogenic factors of different etiology. The gastroprotective effect of the phytocomplex in a dose range of 16-1600 µg/kg was comparable with that of the reference drug plantaglucide and was superior to that of the reference drugs eleutherococcus extract and methyluracil in the therapeutic doses. The antiulcerogenic activity of Lychnis chalcedonica flavonoid complex considerably exceeded activity of Lychnis chalcedonica L. extract demonstrated in our previous experiments.
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Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Úlcera Gástrica
/
Extractos Vegetales
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Antiulcerosos
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Bull Exp Biol Med
Año:
2021
Tipo del documento:
Article