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Benzimidazole-galactosides bind selectively to the Galectin-8 N-Terminal domain: Structure-based design and optimisation.
Hassan, Mujtaba; van Klaveren, Sjors; Håkansson, Maria; Diehl, Carl; Kovacic, Rebeka; Baussière, Floriane; Sundin, Anders P; Dernovsek, Jaka; Walse, Björn; Zetterberg, Fredrik; Leffler, Hakon; Anderluh, Marko; Tomasic, Tihomir; Jakopin, Ziga; Nilsson, Ulf J.
Afiliación
  • Hassan M; Centre for Analysis and Synthesis, Department of Chemistry, Lund University, Box 124, SE-221 00, Lund, Sweden; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000 Ljubljana, Slovenia.
  • van Klaveren S; Centre for Analysis and Synthesis, Department of Chemistry, Lund University, Box 124, SE-221 00, Lund, Sweden; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000 Ljubljana, Slovenia.
  • Håkansson M; SARomics Biostructures AB, Medicon Village, SE-223 81, Lund, Sweden.
  • Diehl C; SARomics Biostructures AB, Medicon Village, SE-223 81, Lund, Sweden.
  • Kovacic R; SARomics Biostructures AB, Medicon Village, SE-223 81, Lund, Sweden.
  • Baussière F; Centre for Analysis and Synthesis, Department of Chemistry, Lund University, Box 124, SE-221 00, Lund, Sweden.
  • Sundin AP; Centre for Analysis and Synthesis, Department of Chemistry, Lund University, Box 124, SE-221 00, Lund, Sweden.
  • Dernovsek J; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000 Ljubljana, Slovenia.
  • Walse B; SARomics Biostructures AB, Medicon Village, SE-223 81, Lund, Sweden.
  • Zetterberg F; Galecto Biotech AB, Sahlgrenska Science Park, Medicinaregatan 8 A, SE-413 46, Gothenburg, Sweden.
  • Leffler H; Department of Laboratory Medicine, Section MIG, Lund University BMC-C1228b, Klinikgatan 28, 221 84, Lund, Sweden.
  • Anderluh M; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000 Ljubljana, Slovenia.
  • Tomasic T; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000 Ljubljana, Slovenia.
  • Jakopin Z; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000 Ljubljana, Slovenia.
  • Nilsson UJ; Centre for Analysis and Synthesis, Department of Chemistry, Lund University, Box 124, SE-221 00, Lund, Sweden. Electronic address: ulf.nilsson@chem.lu.se.
Eur J Med Chem ; 223: 113664, 2021 Nov 05.
Article en En | MEDLINE | ID: mdl-34225180
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Bencimidazoles / Diseño de Fármacos / Galectinas / Galactósidos Idioma: En Revista: Eur J Med Chem Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Bencimidazoles / Diseño de Fármacos / Galectinas / Galactósidos Idioma: En Revista: Eur J Med Chem Año: 2021 Tipo del documento: Article