Is there a hypothalamic basis for anorexia nervosa?
Handb Clin Neurol
; 181: 405-424, 2021.
Article
en En
| MEDLINE
| ID: mdl-34238474
ABSTRACT
The hypothalamus has long been known to control food intake and energy metabolism through a complex network of primary and secondary neurons and glial cells. Anorexia nervosa being a complex disorder characterized by abnormal feeding behavior and food aversion, it is thus quite surprising that not much is known concerning potential hypothalamic modifications in this disorder. In this chapter, we review the recent advances in the fields of genetics, epigenetics, structural and functional imaging, and brain connectivity, as well as neuroendocrine findings and emerging animal models, which have begun to unravel the importance of hypothalamic adaptive processes to our understanding of the pathology of eating disorders.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Anorexia Nerviosa
/
Trastornos de Alimentación y de la Ingestión de Alimentos
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Handb Clin Neurol
Año:
2021
Tipo del documento:
Article