Association of Alcohol and Tobacco Consumption with Depression Severity in the Oldest Old. Results from the Age Different Old Age Cohort Platform.
Int J Environ Res Public Health
; 18(15)2021 07 28.
Article
en En
| MEDLINE
| ID: mdl-34360253
ABSTRACT
This study aimed to examine the association of alcohol and tobacco use with severity of depression in older age. Analyses were performed on a pooled data set (n = 3724) from two German old-age cohort studies (LEILA 75+, 6 follow-ups and AgeCoDe/AgeQualiDe, 9 follow-ups). Depressive symptoms were assessed via two screening scales for depression (CES-D and GDS-15) which were harmonized for pooled analysis. A mixed-effects linear regression model for the total sample and additional stratified models for men and women were used. Smoking at baseline was significantly associated with a higher level of depression severity (ß = 0.142, 95% CI 0.051-0.233, p = 0.002), whereas drinking was significantly associated with a decreased level of depression (ß = -0.069, 95% CI -0.119--0.021, p = 0.005). Concurrent substance use at baseline increased longitudinal depression severity (ß = 0.193, 95% CI 0.011-0.375, p = 0.037). Analyses stratified by gender showed a significant inverse association between drinking and depressive symptoms in men (ß = -0.138, 95% CI -0.231--0.045, p = 0.004), but not in women (ß = -0.060, 95% CI -0.120-0.001, p = 0.052). Given the burden of major depression, it is important that health care providers, especially primary care physicians, assess and monitor lifestyle factors, even at older ages.
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Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Depresión
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Trastorno Depresivo
Tipo de estudio:
Etiology_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Idioma:
En
Revista:
Int J Environ Res Public Health
Año:
2021
Tipo del documento:
Article