The Genomic Architecture of Bladder Exstrophy Epispadias Complex.
Genes (Basel)
; 12(8)2021 07 28.
Article
en En
| MEDLINE
| ID: mdl-34440323
ABSTRACT
The bladder exstrophy-epispadias complex (BEEC) is an abdominal midline malformation comprising a spectrum of congenital genitourinary abnormalities of the abdominal wall, pelvis, urinary tract, genitalia, anus, and spine. The vast majority of BEEC cases are classified as non-syndromic and the etiology of this malformation is still unknown. This review presents the current knowledge on this multifactorial disorder, including phenotypic and anatomical characterization, epidemiology, proposed developmental mechanisms, existing animal models, and implicated genetic and environmental components.
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Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Extrofia de la Vejiga
/
Epispadias
Idioma:
En
Revista:
Genes (Basel)
Año:
2021
Tipo del documento:
Article