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Ssu72 phosphatase directly binds to ZAP-70, thereby providing fine-tuning of TCR signaling and preventing spontaneous inflammation.
Ko, Jae Sung; Jeong, Dongjin; Koh, Jaemoon; Jung, Hyeryeon; Jung, Kyeong Cheon; Jeon, Yoon Kyung; Kim, Hye Young; Yi, Eugene C; Lee, Ho; Lee, Chang-Woo; Chung, Doo Hyun.
Afiliación
  • Ko JS; Laboratory of Immune Regulation, Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.
  • Jeong D; Laboratory of Immune Regulation, Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.
  • Koh J; Department of Pathology, Seoul National University College of Medicine, Seoul 03080, Korea.
  • Jung H; Department of Molecular Medicine and Biopharmaceutical Sciences, School of Convergence Science and Technology, Seoul National University, Seoul 08826, Korea.
  • Jung KC; Department of Pathology, Seoul National University College of Medicine, Seoul 03080, Korea.
  • Jeon YK; Department of Pathology, Seoul National University College of Medicine, Seoul 03080, Korea.
  • Kim HY; Laboratory of Immune Regulation, Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.
  • Yi EC; Department of Molecular Medicine and Biopharmaceutical Sciences, School of Convergence Science and Technology, Seoul National University, Seoul 08826, Korea.
  • Lee H; Graduate School of Cancer Science and Policy, National Cancer Center, Goyang 10408, Korea.
  • Lee CW; Department of Pathology, Seoul National University College of Medicine, Seoul 03080, Korea; doohyun@snu.ac.kr cwlee1234@skku.edu.
  • Chung DH; Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon 2066, Korea.
Proc Natl Acad Sci U S A ; 118(35)2021 08 31.
Article en En | MEDLINE | ID: mdl-34452999
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Receptores de Antígenos de Linfocitos T / Fosfoproteínas Fosfatasas / Linfocitos T CD8-positivos / Proteína Tirosina Quinasa ZAP-70 / Células T de Memoria / Inflamación Tipo de estudio: Etiology_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Receptores de Antígenos de Linfocitos T / Fosfoproteínas Fosfatasas / Linfocitos T CD8-positivos / Proteína Tirosina Quinasa ZAP-70 / Células T de Memoria / Inflamación Tipo de estudio: Etiology_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article