Comparative transcriptomic analysis reveals reproductive impairments caused by PCBs and OH-PCBs through the dysregulation of ER and AR signaling.

Tam, Nathan; Lai, Keng Po; Kong, Richard Yuen Chong

Tam, Nathan; Lai, Keng Po; Kong, Richard Yuen Chong.

Afiliación

Tam N; Department of Chemistry, City University of Hong Kong, Hong Kong, China.
Lai KP; Laboratory of Environmental Pollution and Integrative Omics, Guilin Medical University, Guilin, PR China; Department of Chemistry, City University of Hong Kong, Hong Kong, China; State Key Laboratory of Marine Pollution, City University of Hong Kong, Hong Kong, China. Electronic address: kengplai@cityu.edu.hk.
Kong RYC; Department of Chemistry, City University of Hong Kong, Hong Kong, China; State Key Laboratory of Marine Pollution, City University of Hong Kong, Hong Kong, China. Electronic address: bhrkong@cityu.edu.hk.

Sci Total Environ ; 802: 149913, 2022 Jan 01.

Article en En | MEDLINE | ID: mdl-34474298

Asunto(s)

Bifenilos Policlorados; Reproducción; Estrógenos; Humanos; Células MCF-7; Bifenilos Policlorados/toxicidad; Receptores Androgénicos; Receptores de Estrógenos/genética; Reproducción/efectos de los fármacos; Transducción de Señal; Transcriptoma

Palabras clave

AR; ER; OH-PCBs; PCBs; Pathway; Transcriptome

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Reproducción / Bifenilos Policlorados Idioma: En Revista: Sci Total Environ Año: 2022 Tipo del documento: Article

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