NS398 as a potential drug for autosomal-dominant polycystic kidney disease: Analysis using bioinformatics, and zebrafish and mouse models.

Chen, Sixiu; Huang, Linxi; Zhou, Shoulian; Zhang, Qingzhou; Ruan, Mengna; Fu, Lili; Yang, Bo; Xu, Dechao; Mei, Changlin; Mao, Zhiguo

Chen, Sixiu; Huang, Linxi; Zhou, Shoulian; Zhang, Qingzhou; Ruan, Mengna; Fu, Lili; Yang, Bo; Xu, Dechao; Mei, Changlin; Mao, Zhiguo.

Afiliación

Chen S; Division of Nephrology, Kidney Institute of People's Liberation Army (PLA), Changzheng Hospital, Second Military Medical University, Shanghai, China.
Huang L; Division of Nephrology, Kidney Institute of People's Liberation Army (PLA), Changzheng Hospital, Second Military Medical University, Shanghai, China.
Zhou S; Graduate School of Clinical Medicine, Second Military Medical University, Shanghai, China.
Zhang Q; Division of Nephrology, Kidney Institute of People's Liberation Army (PLA), Changzheng Hospital, Second Military Medical University, Shanghai, China.
Ruan M; Graduate School of Clinical Medicine, Second Military Medical University, Shanghai, China.
Fu L; Division of Nephrology, Kidney Institute of People's Liberation Army (PLA), Changzheng Hospital, Second Military Medical University, Shanghai, China.
Yang B; Division of Nephrology, Kidney Institute of People's Liberation Army (PLA), Changzheng Hospital, Second Military Medical University, Shanghai, China.
Xu D; Division of Nephrology, Kidney Institute of People's Liberation Army (PLA), Changzheng Hospital, Second Military Medical University, Shanghai, China.
Mei C; Internal Medicine â¢ (Nephrology and Endocrinology), Naval Medical Center of PLA, Second Military Medical University, Shanghai, China.
Mao Z; Division of Nephrology, Kidney Institute of People's Liberation Army (PLA), Changzheng Hospital, Second Military Medical University, Shanghai, China.

J Cell Mol Med ; 25(20): 9597-9608, 2021 10.

Article en En | MEDLINE | ID: mdl-34551202

Asunto(s)

Nitrobencenos/farmacología; Riñón Poliquístico Autosómico Dominante/tratamiento farmacológico; Sulfonamidas/farmacología; Animales; Antiinflamatorios no Esteroideos/farmacología; Antiinflamatorios no Esteroideos/uso terapéutico; Biopsia; Biología Computacional/métodos; Inhibidores de la Ciclooxigenasa/farmacología; Inhibidores de la Ciclooxigenasa/uso terapéutico; Bases de Datos Genéticas; Manejo de la Enfermedad; Modelos Animales de Enfermedad; Perfilación de la Expresión Génica; Predisposición Genética a la Enfermedad; Humanos; Redes y Vías Metabólicas; Ratones; Mutación; Nitrobencenos/uso terapéutico; Riñón Poliquístico Autosómico Dominante/genética; Riñón Poliquístico Autosómico Dominante/metabolismo; Riñón Poliquístico Autosómico Dominante/patología; Mapeo de Interacción de Proteínas/métodos; Proteína Quinasa C/genética; Proteína Quinasa C/metabolismo; Sulfonamidas/uso terapéutico

Palabras clave

NS398; autosomal-dominant polycystic kidney disease; bioinformatics analysis; clear-cell renal cell carcinoma; cystogenesis

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Sulfonamidas / Riñón Poliquístico Autosómico Dominante / Nitrobencenos Idioma: En Revista: J Cell Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2021 Tipo del documento: Article

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