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SIRPα-αCD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells.
Tahk, Siret; Vick, Binje; Hiller, Björn; Schmitt, Saskia; Marcinek, Anetta; Perini, Enrico D; Leutbecher, Alexandra; Augsberger, Christian; Reischer, Anna; Tast, Benjamin; Humpe, Andreas; Jeremias, Irmela; Subklewe, Marion; Fenn, Nadja C; Hopfner, Karl-Peter.
Afiliación
  • Tahk S; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Feodor-Lynen-Straße 25, 81377, Munich, Germany.
  • Vick B; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Neuherberg, Germany.
  • Hiller B; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.
  • Schmitt S; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Feodor-Lynen-Straße 25, 81377, Munich, Germany.
  • Marcinek A; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Feodor-Lynen-Straße 25, 81377, Munich, Germany.
  • Perini ED; Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich, Munich, Germany.
  • Leutbecher A; Department of Hematology and Oncology, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.
  • Augsberger C; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Feodor-Lynen-Straße 25, 81377, Munich, Germany.
  • Reischer A; Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich, Munich, Germany.
  • Tast B; Department of Hematology and Oncology, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.
  • Humpe A; Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich, Munich, Germany.
  • Jeremias I; Department of Hematology and Oncology, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.
  • Subklewe M; Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich, Munich, Germany.
  • Fenn NC; Department of Hematology and Oncology, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.
  • Hopfner KP; Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich, Munich, Germany.
J Hematol Oncol ; 14(1): 155, 2021 09 27.
Article en En | MEDLINE | ID: mdl-34579739

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Receptores Inmunológicos / Leucemia Mieloide Aguda / Antígenos de Diferenciación / Antígeno CD47 / Subunidad alfa del Receptor de Interleucina-3 / Antineoplásicos Inmunológicos Idioma: En Revista: J Hematol Oncol Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2021 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Receptores Inmunológicos / Leucemia Mieloide Aguda / Antígenos de Diferenciación / Antígeno CD47 / Subunidad alfa del Receptor de Interleucina-3 / Antineoplásicos Inmunológicos Idioma: En Revista: J Hematol Oncol Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2021 Tipo del documento: Article