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Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.
Panwalkar, Pooja; Tamrazi, Benita; Dang, Derek; Chung, Chan; Sweha, Stefan; Natarajan, Siva Kumar; Pun, Matthew; Bayliss, Jill; Ogrodzinski, Martin P; Pratt, Drew; Mullan, Brendan; Hawes, Debra; Yang, Fusheng; Lu, Chao; Sabari, Benjamin R; Achreja, Abhinav; Heon, Jin; Animasahun, Olamide; Cieslik, Marcin; Dunham, Christopher; Yip, Stephen; Hukin, Juliette; Phillips, Joanna J; Bornhorst, Miriam; Griesinger, Andrea M; Donson, Andrew M; Foreman, Nicholas K; Garton, Hugh J L; Heth, Jason; Muraszko, Karin; Nazarian, Javad; Koschmann, Carl; Jiang, Li; Filbin, Mariella G; Nagrath, Deepak; Kool, Marcel; Korshunov, Andrey; Pfister, Stefan M; Gilbertson, Richard J; Allis, C David; Chinnaiyan, Arul M; Lunt, Sophia Y; Blüml, Stefan; Judkins, Alexander R; Venneti, Sriram.
Afiliación
  • Panwalkar P; Laboratory of Brain Tumor Metabolism and Epigenetics, Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Tamrazi B; Department of Radiology, Children's Hospital Los Angeles, Keck School of Medicine University of Southern California, Los Angeles, CA 90027, USA.
  • Dang D; Laboratory of Brain Tumor Metabolism and Epigenetics, Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Chung C; Department of New Biology, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Korea.
  • Sweha S; Laboratory of Brain Tumor Metabolism and Epigenetics, Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Natarajan SK; Laboratory of Brain Tumor Metabolism and Epigenetics, Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Pun M; Laboratory of Brain Tumor Metabolism and Epigenetics, Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Bayliss J; Laboratory of Brain Tumor Metabolism and Epigenetics, Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Ogrodzinski MP; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824, USA.
  • Pratt D; Department of Physiology, Michigan State University, East Lansing, MI 48824, USA.
  • Mullan B; Laboratory of Brain Tumor Metabolism and Epigenetics, Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Hawes D; Department of Pediatrics, Michigan Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
  • Yang F; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Keck School of Medicine University of Southern California, Los Angeles, CA 90027, USA.
  • Lu C; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Keck School of Medicine University of Southern California, Los Angeles, CA 90027, USA.
  • Sabari BR; Department of Genetics and Development and Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Achreja A; Laboratory of Chromatin Biology and Epigenetics, Rockefeller University, New York, NY 10065, USA.
  • Heon J; Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
  • Animasahun O; Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109, USA.
  • Cieslik M; Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
  • Dunham C; Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109, USA.
  • Yip S; Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
  • Hukin J; Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109, USA.
  • Phillips JJ; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
  • Bornhorst M; Laboratory of Brain Tumor Metabolism and Epigenetics, Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Griesinger AM; Division of Anatomic Pathology, British Columbia Children's Hospital, Vancouver, British Columbia V6H 3N1, Canada.
  • Donson AM; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
  • Foreman NK; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
  • Garton HJL; Division of Hematology and Oncology, Children's and Women's Health Centre of B.C., University of British Columbia, Vancouver, British Columbia V6H 3N1, Canada.
  • Heth J; Department of Pathology, University of California San Francisco, San Francisco, CA 94132, USA.
  • Muraszko K; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94132, USA.
  • Nazarian J; Research Center for Genetic Medicine, Children's National Health System, Washington, DC 20012, USA.
  • Koschmann C; Brain Tumor Institute, Children's National Health System, Washington, DC 20012, USA.
  • Jiang L; Department of Pediatrics, University of Colorado, Denver, Aurora, CO 80045, USA.
  • Filbin MG; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, CO 80045, USA.
  • Nagrath D; Department of Pediatrics, University of Colorado, Denver, Aurora, CO 80045, USA.
  • Kool M; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, CO 80045, USA.
  • Korshunov A; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, CO 80045, USA.
  • Pfister SM; Department of Neurosurgery, University of Michigan, Ann Arbor, MI 48109, USA.
  • Gilbertson RJ; Department of Neurosurgery, University of Michigan, Ann Arbor, MI 48109, USA.
  • Allis CD; Department of Neurosurgery, University of Michigan, Ann Arbor, MI 48109, USA.
  • Chinnaiyan AM; Department of Neurosurgery, University of Michigan, Ann Arbor, MI 48109, USA.
  • Lunt SY; Research Center for Genetic Medicine, Children's National Health System, Washington, DC 20012, USA.
  • Blüml S; Brain Tumor Institute, Children's National Health System, Washington, DC 20012, USA.
  • Judkins AR; DMG Research Center, Department of Oncology, University Children's Hospital, CH-8032 Zürich, Switzerland.
  • Venneti S; Department of Pediatrics, Michigan Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Sci Transl Med ; 13(614): eabc0497, 2021 Oct 06.
Article en En | MEDLINE | ID: mdl-34613815
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Histonas / Ependimoma Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Histonas / Ependimoma Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2021 Tipo del documento: Article