Reversing tumor immunosuppressive microenvironment via targeting codelivery of CpG ODNs/PD-L1 peptide antagonists to enhance the immune checkpoint blockade-based anti-tumor effect.

Zhang, Min; Fang, Zhou; Zhang, Haitao; Cui, Mingxiao; Wang, Mingfu; Liu, Kehai

Zhang, Min; Fang, Zhou; Zhang, Haitao; Cui, Mingxiao; Wang, Mingfu; Liu, Kehai.

Afiliación

Zhang M; Department of Biopharmacy, Shanghai Ocean University, Hucheng Ring Road, Shanghai 201306, China.
Fang Z; Department of Biopharmacy, Shanghai Ocean University, Hucheng Ring Road, Shanghai 201306, China.
Zhang H; Department of Biopharmacy, Shanghai Ocean University, Hucheng Ring Road, Shanghai 201306, China.
Cui M; Department of Biopharmacy, Shanghai Ocean University, Hucheng Ring Road, Shanghai 201306, China.
Wang M; Department of Biopharmacy, Shanghai Ocean University, Hucheng Ring Road, Shanghai 201306, China; School of biological sciences, University Hong Kong, Pokfulam Road, Hong Kong, 999077, China.
Liu K; Department of Biopharmacy, Shanghai Ocean University, Hucheng Ring Road, Shanghai 201306, China. Electronic address: khliu@shou.edu.cn.

Eur J Pharm Sci ; 168: 106044, 2022 Jan 01.

Article en En | MEDLINE | ID: mdl-34666183

Asunto(s)

Antígeno B7-H1; Microambiente Tumoral; Inhibidores de Puntos de Control Inmunológico; Receptor de Manosa; Péptidos/farmacología

Palabras clave

Co-delivey; CpG ODNs; Hyaluronic acid; Immune checkpoint; PD-L1; liposome

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Microambiente Tumoral / Antígeno B7-H1 Idioma: En Revista: Eur J Pharm Sci Asunto de la revista: FARMACIA / FARMACOLOGIA / QUIMICA Año: 2022 Tipo del documento: Article

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