The NO-dependent caspase signaling pathway is a target of deoxynivalenol in growth inhibition in vitro.

Guo, Pu; Lu, Qirong; Hu, Siyi; Martínez, María-Aránzazu; Lopez-Torres, Bernardo; Martínez, Marta; Martínez-Larrañaga, María-Rosa; Wang, Xu; Anadón, Arturo; Ares, Irma

Guo, Pu; Lu, Qirong; Hu, Siyi; Martínez, María-Aránzazu; Lopez-Torres, Bernardo; Martínez, Marta; Martínez-Larrañaga, María-Rosa; Wang, Xu; Anadón, Arturo; Ares, Irma.

Afiliación

Guo P; National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues, Huazhong Agricultural University, Wuhan, Hubei, 430070, China; MAO Laboratory for Risk Assessment of Quality and Safety of Livestock and Poultry Products, Huazhong Agric
Lu Q; National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues, Huazhong Agricultural University, Wuhan, Hubei, 430070, China; MAO Laboratory for Risk Assessment of Quality and Safety of Livestock and Poultry Products, Huazhong Agric
Hu S; National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues, Huazhong Agricultural University, Wuhan, Hubei, 430070, China; MAO Laboratory for Risk Assessment of Quality and Safety of Livestock and Poultry Products, Huazhong Agric
Martínez MA; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Universidad Complutense de Madrid, 28040, Madrid, Spain.
Lopez-Torres B; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Universidad Complutense de Madrid, 28040, Madrid, Spain.
Martínez M; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Universidad Complutense de Madrid, 28040, Madrid, Spain.
Martínez-Larrañaga MR; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Universidad Complutense de Madrid, 28040, Madrid, Spain.
Wang X; National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues, Huazhong Agricultural University, Wuhan, Hubei, 430070, China; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Universidad Complutense de Madr
Anadón A; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Universidad Complutense de Madrid, 28040, Madrid, Spain. Electronic address: aanadon@ucm.es.
Ares I; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Universidad Complutense de Madrid, 28040, Madrid, Spain.

Food Chem Toxicol ; 158: 112629, 2021 Dec.

Article en En | MEDLINE | ID: mdl-34673182

Asunto(s)

Caspasas/metabolismo; Contaminación de Alimentos; Trastornos del Crecimiento/metabolismo; Mitocondrias/efectos de los fármacos; Óxido Nítrico/metabolismo; Estrés Oxidativo/efectos de los fármacos; Tricotecenos/toxicidad; Clorometilcetonas de Aminoácidos/farmacología; Animales; Apoptosis; Línea Celular Tumoral; Niño; Preescolar; Exposición a Riesgos Ambientales/efectos adversos; Trastornos del Crecimiento/inducido químicamente; Hormona del Crecimiento/metabolismo; Hormona Liberadora de Hormona del Crecimiento/metabolismo; Hemoglobinas/farmacología; Humanos; Lactante; Interleucinas/metabolismo; Óxido Nítrico Sintasa/metabolismo; Ratas; Especies Reactivas de Oxígeno/metabolismo; Transducción de Señal

Palabras clave

Caspase signaling pathway; Deoxynivalenol; GHRH; Growth inhibition; Interleukins; Mitochondrial damage

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tricotecenos / Contaminación de Alimentos / Estrés Oxidativo / Caspasas / Trastornos del Crecimiento / Mitocondrias / Óxido Nítrico Idioma: En Revista: Food Chem Toxicol Año: 2021 Tipo del documento: Article

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