Heavy mutagenesis by tobacco leads to lung adenocarcinoma tumors with KRAS G12 mutations other than G12D, leading KRAS G12D tumors-on average-to exhibit a lower mutation burden.

Tan, Chichun; Mandell, Jeffrey D; Dasari, Krishna; Cannataro, Vincent L; Alfaro-Murillo, Jorge A; Townsend, Jeffrey P

Tan, Chichun; Mandell, Jeffrey D; Dasari, Krishna; Cannataro, Vincent L; Alfaro-Murillo, Jorge A; Townsend, Jeffrey P.

Afiliación

Tan C; Department of Biostatistics, Yale School of Public Health, New Haven, CT, United States.
Mandell JD; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, United States.
Dasari K; Yale College, New Haven, CT, United States.
Cannataro VL; Department of Biology, Emmanuel College, Boston, MA, United States.
Alfaro-Murillo JA; Department of Biostatistics, Yale School of Public Health, New Haven, CT, United States.
Townsend JP; Department of Biostatistics, Yale School of Public Health, New Haven, CT, United States; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, United States; Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, United States. Electronic addre

Lung Cancer ; 166: 265-269, 2022 04.

Article en En | MEDLINE | ID: mdl-34736794

Asunto(s)

Adenocarcinoma del Pulmón; Adenocarcinoma; Neoplasias Pulmonares; Adenocarcinoma/genética; Adenocarcinoma/patología; Adenocarcinoma del Pulmón/genética; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/patología; Mutagénesis; Mutación; Proteínas Proto-Oncogénicas p21(ras)/genética; Nicotiana

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Adenocarcinoma / Adenocarcinoma del Pulmón / Neoplasias Pulmonares Idioma: En Revista: Lung Cancer Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article

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