Management of Pulmonary Mucormycosis After Orthotopic Heart Transplant: A Case Series.
Transplant Proc
; 53(10): 3051-3055, 2021 Dec.
Article
en En
| MEDLINE
| ID: mdl-34772489
ABSTRACT
Invasive pulmonary mucormycosis is a potentially fatal infection that can occur in immunosuppressed patients such as those who have undergone orthotopic heart transplant (OHT). High-dose intravenous antifungal agents, including amphotericin B, are generally accepted as the first-line medical treatment, with prompt surgical resection of lesions if feasible. The body of evidence guiding treatment decisions, however, is sparse, particularly regarding adjustment of immunosuppression during acute infection and long-term recovery. We present 2 cases of patients with pulmonary mucormycosis occurring within the first 6 months after OHT, both of whom successfully recovered after appropriate medical and surgical treatment, and we highlight differences in immunosuppression management strategies for this life-threatening condition.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Trasplante de Corazón
/
Mucormicosis
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
Idioma:
En
Revista:
Transplant Proc
Año:
2021
Tipo del documento:
Article