Parecoxib ameliorates renal toxicity and injury in sepsis-induced mouse model and LPS-induced HK-2 cells.

Guo, Yuanyuan; Wu, Bin; Chen, Qibin; Min, Su

Guo, Yuanyuan; Wu, Bin; Chen, Qibin; Min, Su.

Afiliación

Guo Y; Department of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Wu B; Department of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Chen Q; Department of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Min S; Department of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.

Drug Dev Res ; 83(3): 659-668, 2022 05.

Article en En | MEDLINE | ID: mdl-34813666

Asunto(s)

Lesión Renal Aguda; Sepsis; Lesión Renal Aguda/inducido químicamente; Lesión Renal Aguda/tratamiento farmacológico; Lesión Renal Aguda/metabolismo; Animales; Apoptosis; Ciclooxigenasa 2; Modelos Animales de Enfermedad; Quinasa I-kappa B; Inflamación/metabolismo; Isoxazoles; Lipopolisacáridos/farmacología; Ratones; FN-kappa B/metabolismo; Sepsis/complicaciones; Sepsis/tratamiento farmacológico; Sepsis/metabolismo

Palabras clave

COX-2; Parecoxib; kidney injury; renal function; sepsis

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Sepsis / Lesión Renal Aguda Tipo de estudio: Prognostic_studies Idioma: En Revista: Drug Dev Res Año: 2022 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google