Age-related type I collagen modifications reveal tissue-defining differences between ligament and tendon.

Hudson, David M; Archer, Marilyn; Rai, Jyoti; Weis, MaryAnn; Fernandes, Russell J; Eyre, David R.

Afiliación

Hudson DM; Department of Orthopaedics and Sports Medicine, University of Washington, Seattle, WA, United States.
Archer M; Department of Orthopaedics and Sports Medicine, University of Washington, Seattle, WA, United States.
Rai J; Department of Orthopaedics and Sports Medicine, University of Washington, Seattle, WA, United States.
Weis M; Department of Orthopaedics and Sports Medicine, University of Washington, Seattle, WA, United States.
Fernandes RJ; Department of Orthopaedics and Sports Medicine, University of Washington, Seattle, WA, United States.
Eyre DR; Department of Orthopaedics and Sports Medicine, University of Washington, Seattle, WA, United States.

Matrix Biol Plus ; 12: 100070, 2021 Dec.

Article en En | MEDLINE | ID: mdl-34825162

Palabras clave

ACL, Anterior cruciate ligament; Collagen; Cross-linking; DHLNL, dehydrohydroxylysinonorleucine; HHL, histidinohydroxylysinonorleucine; HHMD, histidinohydroxymerodesmosine; HLNL, hydroxylysinonorleucine; HP, hydroxylysine pyridinoline; LC, liquid chromatography; LCL, lateral collateral ligament; LP, lysine pyridinoline; Ligament; MCL, medial collateral ligament; MS, mass spectrometry; Mass spectrometry; P3H1, prolyl 3-hydroxylase 1; P3H2, prolyl 3-hydroxylase 2; PCL, posterior cruciate ligament; Post-translational modifications; QT, quadriceps tendon; Tendon