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Spatial and Temporal Trends of SARS-CoV-2 RNA from Wastewater Treatment Plants over 6 Weeks in Cape Town, South Africa.
Street, Renée; Mathee, Angela; Mangwana, Noluxabiso; Dias, Stephanie; Sharma, Jyoti Rajan; Ramharack, Pritika; Louw, Johan; Reddy, Tarylee; Brocker, Ludwig; Surujlal-Naicker, Swastika; Berkowitz, Natacha; Malema, Mokaba Shirley; Nkambule, Sizwe; Webster, Candice; Mahlangeni, Nomfundo; Gelderblom, Huub; Mdhluli, Mongezi; Gray, Glenda; Muller, Christo; Johnson, Rabia.
Afiliación
  • Street R; Environment & Health Research Unit, South African Medical Research Council (SAMRC), Tygerberg 7505, South Africa.
  • Mathee A; Environment & Health Research Unit, South African Medical Research Council (SAMRC), Tygerberg 7505, South Africa.
  • Mangwana N; Environmental Health Department, Faculty of Health Sciences, University of Johannesburg, Johannesburg 2092, South Africa.
  • Dias S; Biomedical Research and Innovation Platform (BRIP), South African Medical Research Council (SAMRC), Tygerberg 7505, South Africa.
  • Sharma JR; Department of Microbiology, Stellenbosch University, Stellenbosch 7600, South Africa.
  • Ramharack P; Biomedical Research and Innovation Platform (BRIP), South African Medical Research Council (SAMRC), Tygerberg 7505, South Africa.
  • Louw J; Biomedical Research and Innovation Platform (BRIP), South African Medical Research Council (SAMRC), Tygerberg 7505, South Africa.
  • Reddy T; Biomedical Research and Innovation Platform (BRIP), South African Medical Research Council (SAMRC), Tygerberg 7505, South Africa.
  • Brocker L; Biomedical Research and Innovation Platform (BRIP), South African Medical Research Council (SAMRC), Tygerberg 7505, South Africa.
  • Surujlal-Naicker S; Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa 3886, South Africa.
  • Berkowitz N; Biostatistics Unit, South African Medical Research Council (SAMRC), Tygerberg 7505, South Africa.
  • Malema MS; Department of Microbiology, Stellenbosch University, Stellenbosch 7600, South Africa.
  • Nkambule S; Scientific Services, Water and Sanitation Department, City of Cape Town Metropolitan Municipality, Cape Town 8000, South Africa.
  • Webster C; Community Services and Health, City Health, City of Cape Town, Hertzog Boulevard, Cape Town 8001, South Africa.
  • Mahlangeni N; Environment & Health Research Unit, South African Medical Research Council (SAMRC), Tygerberg 7505, South Africa.
  • Gelderblom H; Environment & Health Research Unit, South African Medical Research Council (SAMRC), Tygerberg 7505, South Africa.
  • Mdhluli M; Environment & Health Research Unit, South African Medical Research Council (SAMRC), Tygerberg 7505, South Africa.
  • Gray G; Environment & Health Research Unit, South African Medical Research Council (SAMRC), Tygerberg 7505, South Africa.
  • Muller C; COVID-19 Prevention Network (COVPN), Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Johnson R; Office of the President, South African Medical Research Council, Tygerberg 7050, South Africa.
Article en En | MEDLINE | ID: mdl-34831841
ABSTRACT
Recent scientific trends have revealed that the collection and analysis of data on the occurrence and fate of SARS-CoV-2 in wastewater may serve as an early warning system for COVID-19. In South Africa, the first COVID-19 epicenter emerged in the Western Cape Province. The City of Cape Town, located in the Western Cape Province, has approximately 4 million inhabitants. This study reports on the monitoring of SARS-CoV-2 RNA in the wastewater of the City of Cape Town's wastewater treatment plants (WWTPs) during the peak of the epidemic. During this period, the highest overall median viral RNA signal was observed in week 1 (9200 RNA copies/mL) and declined to 127 copies/mL in week 6. The overall decrease in the amount of detected viral SARS-CoV-2 RNA over the 6-week study period was associated with a declining number of newly identified COVID-19 cases in the city. The SARS-CoV-2 early warning system has now been established to detect future waves of COVID-19.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Purificación del Agua / COVID-19 País/Región como asunto: Africa Idioma: En Revista: Int J Environ Res Public Health Año: 2021 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Purificación del Agua / COVID-19 País/Región como asunto: Africa Idioma: En Revista: Int J Environ Res Public Health Año: 2021 Tipo del documento: Article