Vesicular IFN-Î³ as a cooperative attacker to enhance anti-cancer effect of 5-fluorouracil via thymidine phosphorylase upregulation and tumor microenvironment normalization.

Peng, Yan; Hu, Yumiao; Qiu, Liyan

Peng, Yan; Hu, Yumiao; Qiu, Liyan.

Afiliación

Peng Y; Ministry of Education (MOE) Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, People's Republic of China.
Hu Y; Ministry of Education (MOE) Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, People's Republic of China.
Qiu L; Ministry of Education (MOE) Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, People's Republic of China. Electronic address: lyqiu@zju.edu.cn.

Nanomedicine ; 40: 102501, 2022 02.

Article en En | MEDLINE | ID: mdl-34843983

Asunto(s)

Neoplasias del Colon; Fluorouracilo; Neoplasias del Colon/patología; Fluorouracilo/farmacología; Humanos; Interferón gamma/metabolismo; Timidina Fosforilasa/genética; Timidina Fosforilasa/metabolismo; Microambiente Tumoral; Regulación hacia Arriba

Palabras clave

5-Fluorouracil; Combination therapy; Immunoregulation; Interferon-Î³; Self-assembled nano-vesicle

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias del Colon / Fluorouracilo Idioma: En Revista: Nanomedicine Asunto de la revista: BIOTECNOLOGIA Año: 2022 Tipo del documento: Article

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