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The FusX TALE Base Editor (FusXTBE) for Rapid Mitochondrial DNA Programming of Human Cells In Vitro and Zebrafish Disease Models In Vivo.
Sabharwal, Ankit; Kar, Bibekananda; Restrepo-Castillo, Santiago; Holmberg, Shannon R; Mathew, Neal D; Kendall, Benjamin Luke; Cotter, Ryan P; WareJoncas, Zachary; Seiler, Christoph; Nakamaru-Ogiso, Eiko; Clark, Karl J; Ekker, Stephen C.
Afiliación
  • Sabharwal A; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.
  • Kar B; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.
  • Restrepo-Castillo S; Mayo Clinic Graduate School of Biomedical Sciences, Virology and Gene Therapy Track, Mayo Clinic, Rochester, Minnesota, USA.
  • Holmberg SR; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.
  • Mathew ND; Mitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Kendall BL; Mayo Clinic Graduate School of Biomedical Sciences, Virology and Gene Therapy Track, Mayo Clinic, Rochester, Minnesota, USA.
  • Cotter RP; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.
  • WareJoncas Z; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.
  • Seiler C; Zebrafish Core, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Nakamaru-Ogiso E; Mitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Clark KJ; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
  • Ekker SC; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.
CRISPR J ; 4(6): 799-821, 2021 12.
Article en En | MEDLINE | ID: mdl-34847747
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pez Cebra / ADN Mitocondrial Idioma: En Revista: CRISPR J Año: 2021 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pez Cebra / ADN Mitocondrial Idioma: En Revista: CRISPR J Año: 2021 Tipo del documento: Article